Clarithromycin | Fromilide Uno tablets retard 500 mg, 14 pcs.
Special Price
$25.48
Regular Price
$33.00
In stock
SKU
BID463708
Release form
Extended-release tablets, film-coated
Extended-release tablets, film-coated
Release form
Extended-release tablets, film-coated
Packing
14 pcs.
Pharmacological action
Fromilide Uno is a semi-synthetic antibiotic from the macrolide group. It inhibits protein synthesis in a microbial cell, has a bacteriostatic (mainly) and bactericidal effect.
Indications
- Upper respiratory tract infections including: tonsillopharyngitis, acute sinusitis.
- Otitis media.
- Lower respiratory tract infections.
- Infections of the skin and soft tissues.
- Infections caused by mycobacteria, including: Mycobacterium avium complex, Mycobacterium kansasii, Mycobacterium mannum, Mycobacterium leprae.
- Other infectious and inflammatory diseases caused by drug-sensitive microorganisms.
- Eradication of Helicobacter pylori and a decrease in the frequency of relapse of duodenal ulcer (as part of combination therapy).
Contraindications
- Severe liver failure.
- Hepatitis (history).
- Porfiry.
- I trimester of pregnancy.
- Lactation.
- Concomitant use with terfenadine, cisapride, pimozide or astemizole.
- Hypersensitivity to clarithromycin or other macrolide antibiotics.
Use during pregnancy and lactation
The use of the drug in the first trimester of pregnancy is contraindicated. The use of the drug in the II and III trimesters of pregnancy is possible only if the intended benefit to the mother outweighs the potential risk to the fetus. Clarithromycin is excreted in breast milk, so if you need to use the drug during lactation, breastfeeding should be discontinued.
Special instructions
Care should be taken with Fromilid Uno against drugs metabolized by the liver (it is recommended to measure their concentration in the blood). With simultaneous use with warfarin or other indirect anticoagulants, it is necessary to control prothrombin time. Attention should be paid to the possibility of cross-resistance between clarithromycin and other macrolide antibiotics, as well as lincomycin and clindamycin. In severe persistent diarrhea, which may indicate pseudomembranous colitis, you should stop taking the drug and consult your doctor.
Composition
In 1 tablet of prolonged action, film-coated contains: clarithromycin 500 mg.
Excipients: sodium alginate, sodium calcium alginate, lactose monohydrate, povidone, polysorbate 80, anhydrous colloidal silicon dioxide, magnesium stearate, talc, hypromellose, quinoline yellow dye (E104), titanium dioxide (E171), propylene glycol.
Dosage and administration
Tablets should be taken with meals: swallow whole, do not break with a small amount of liquid. Adults and children over the age of 12 years are prescribed 500 mg / day (1 tablet). For the treatment of severe infections, the daily dose is increased to 1000 mg / day (2 tablets). The duration of treatment is usually 7-14 days.
Composition of
1 g of the preparation contains:
Active ingredient:
Choline salicylate - 0.200 g
Excipients:
Glycerol - 0.130 g
Ethanol 96% - 0.100 g
Chlorobutfr gtr brbf100 gt4444 actions of
From the digestive system: nausea, vomiting, diarrhea (with severe and persistent diarrhea, which may be due to pseudomembranous colitis, the drug should be canceled), abdominal pain, stomatitis, glossitis, a transient change in taste sensations is very rare - an increase in ciency liver enzymes cholestatic jaundice.
From the side of the central nervous system and peripheral nervous system: headache in some cases - dizziness, confusion, fear, insomnia, nightmares.
From the cardiovascular system: very rarely - lengthening of the QT interval, ventricular arrhythmia (including ventricular paroxysmal tachycardia, trembling or ventricular fibrillation).
Allergic reactions: hypersensitivity reactions (including urticaria, anaphylaxis) are very rare - Stevens-Johnson syndrome.
Most patients have low-intensity side effects. In case of side effects, consult your doctor.
Drug Interactions
Clarithromycin is metabolized in the liver, where it can inhibit the action of isoenzymes of the cytochrome P450 system. With the simultaneous use of clarithromycin with drugs, metabolized by the P450 cytochrome system, concentrations of the latter can increase and cause side effects. Therefore, terfenadine, cisapride, pimozide and astemizole should not be used during treatment with clarithromycin because of the threat of life-threatening arrhythmias. Prothrombin time should be periodically monitored in patients receiving clarithromycin concomitantly with warfarin or other oral anticoagulants. The simultaneous use of clarithromycin and zidovudine reduces the absorption of zidovudine. The simultaneous use of clarithromycin and ritonavir leads to a significant increase in the level of clarithromycin in serum and a significant decrease in the level of its metabolite in serum.
Overdose
Symptoms: nausea, vomiting, diarrhea, headache, confusion.
Treatment: Wash your stomach immediately. Symptomatic treatment. Hemodialysis and peritoneal dialysis do not lead to a significant change in serum clarithromycin levels.
Storage Conditions
Store in a cool cool place.
active substance
Clarithromycin
Terms leave through pharmacies
In retseptu
Dosage form
tablet prolong.
For
For children older than 12 years, Adults as prescribed by the doctor, Pregnant II and III trimester as prescribed by the doctor, For children as prescribed
Indications
Indications
From sore throat, Vaginal infections, Postpartum infections, From tonsillitis, From otitis media, 5 otitis infection, Prophylactic infection, Draft5 Indications
Indications
From angina, From sinusitis, From skin infections, From pharyngitis, Colds, From tonsillitis, From boils, From stomach and duodenal ulcers, From respiratory infections, From gastrointestinal tract infections caused by Helicobacter pylori, Br onchitis, From otitis media
KRKA d.d. Novo mesto AO, Slovenia
Extended-release tablets, film-coated
Packing
14 pcs.
Pharmacological action
Fromilide Uno is a semi-synthetic antibiotic from the macrolide group. It inhibits protein synthesis in a microbial cell, has a bacteriostatic (mainly) and bactericidal effect.
Indications
- Upper respiratory tract infections including: tonsillopharyngitis, acute sinusitis.
- Otitis media.
- Lower respiratory tract infections.
- Infections of the skin and soft tissues.
- Infections caused by mycobacteria, including: Mycobacterium avium complex, Mycobacterium kansasii, Mycobacterium mannum, Mycobacterium leprae.
- Other infectious and inflammatory diseases caused by drug-sensitive microorganisms.
- Eradication of Helicobacter pylori and a decrease in the frequency of relapse of duodenal ulcer (as part of combination therapy).
Contraindications
- Severe liver failure.
- Hepatitis (history).
- Porfiry.
- I trimester of pregnancy.
- Lactation.
- Concomitant use with terfenadine, cisapride, pimozide or astemizole.
- Hypersensitivity to clarithromycin or other macrolide antibiotics.
Use during pregnancy and lactation
The use of the drug in the first trimester of pregnancy is contraindicated. The use of the drug in the II and III trimesters of pregnancy is possible only if the intended benefit to the mother outweighs the potential risk to the fetus. Clarithromycin is excreted in breast milk, so if you need to use the drug during lactation, breastfeeding should be discontinued.
Special instructions
Care should be taken with Fromilid Uno against drugs metabolized by the liver (it is recommended to measure their concentration in the blood). With simultaneous use with warfarin or other indirect anticoagulants, it is necessary to control prothrombin time. Attention should be paid to the possibility of cross-resistance between clarithromycin and other macrolide antibiotics, as well as lincomycin and clindamycin. In severe persistent diarrhea, which may indicate pseudomembranous colitis, you should stop taking the drug and consult your doctor.
Composition
In 1 tablet of prolonged action, film-coated contains: clarithromycin 500 mg.
Excipients: sodium alginate, sodium calcium alginate, lactose monohydrate, povidone, polysorbate 80, anhydrous colloidal silicon dioxide, magnesium stearate, talc, hypromellose, quinoline yellow dye (E104), titanium dioxide (E171), propylene glycol.
Dosage and administration
Tablets should be taken with meals: swallow whole, do not break with a small amount of liquid. Adults and children over the age of 12 years are prescribed 500 mg / day (1 tablet). For the treatment of severe infections, the daily dose is increased to 1000 mg / day (2 tablets). The duration of treatment is usually 7-14 days.
Composition of
1 g of the preparation contains:
Active ingredient:
Choline salicylate - 0.200 g
Excipients:
Glycerol - 0.130 g
Ethanol 96% - 0.100 g
Chlorobutfr gtr brbf100 gt4444 actions of
From the digestive system: nausea, vomiting, diarrhea (with severe and persistent diarrhea, which may be due to pseudomembranous colitis, the drug should be canceled), abdominal pain, stomatitis, glossitis, a transient change in taste sensations is very rare - an increase in ciency liver enzymes cholestatic jaundice.
From the side of the central nervous system and peripheral nervous system: headache in some cases - dizziness, confusion, fear, insomnia, nightmares.
From the cardiovascular system: very rarely - lengthening of the QT interval, ventricular arrhythmia (including ventricular paroxysmal tachycardia, trembling or ventricular fibrillation).
Allergic reactions: hypersensitivity reactions (including urticaria, anaphylaxis) are very rare - Stevens-Johnson syndrome.
Most patients have low-intensity side effects. In case of side effects, consult your doctor.
Drug Interactions
Clarithromycin is metabolized in the liver, where it can inhibit the action of isoenzymes of the cytochrome P450 system. With the simultaneous use of clarithromycin with drugs, metabolized by the P450 cytochrome system, concentrations of the latter can increase and cause side effects. Therefore, terfenadine, cisapride, pimozide and astemizole should not be used during treatment with clarithromycin because of the threat of life-threatening arrhythmias. Prothrombin time should be periodically monitored in patients receiving clarithromycin concomitantly with warfarin or other oral anticoagulants. The simultaneous use of clarithromycin and zidovudine reduces the absorption of zidovudine. The simultaneous use of clarithromycin and ritonavir leads to a significant increase in the level of clarithromycin in serum and a significant decrease in the level of its metabolite in serum.
Overdose
Symptoms: nausea, vomiting, diarrhea, headache, confusion.
Treatment: Wash your stomach immediately. Symptomatic treatment. Hemodialysis and peritoneal dialysis do not lead to a significant change in serum clarithromycin levels.
Storage Conditions
Store in a cool cool place.
active substance
Clarithromycin
Terms leave through pharmacies
In retseptu
Dosage form
tablet prolong.
For
For children older than 12 years, Adults as prescribed by the doctor, Pregnant II and III trimester as prescribed by the doctor, For children as prescribed
Indications
Indications
From sore throat, Vaginal infections, Postpartum infections, From tonsillitis, From otitis media, 5 otitis infection, Prophylactic infection, Draft5 Indications
Indications
From angina, From sinusitis, From skin infections, From pharyngitis, Colds, From tonsillitis, From boils, From stomach and duodenal ulcers, From respiratory infections, From gastrointestinal tract infections caused by Helicobacter pylori, Br onchitis, From otitis media
KRKA d.d. Novo mesto AO, Slovenia
Write Your Own Review