Buy Afrin Moisturizing Nasal Spray for Rhinitis, 15 ml, Bayer

Description

Dosage form

Nasal spray: a white or almost white gel-like suspension with a characteristic citrus odor.

Structure

Active ingredient: oxymetazoline hydrochloride 0.5 mg.

Nasal spray

Excipients: microcrystalline cellulose and sodium carmellose (Avicel RC-591) 30 mg, sodium hydrogen phosphate 0.975 mg, sodium dihydrogen phosphate monohydrate 5.525 mg, disodium edetate dihydrate 0.3 mg, macrogol-1450 50 mg, povidone-K29-32 30 mg, benzyl alcohol 2.5 mg, lemon flavor 1.5 mg, benzalkonium chloride solution 17% 1.471 mg, glycerol 5 mg, purified water qs up to 1 ml.

pharmachologic effect

Topical alpha adrenergic stimulant.

Has a vasoconstrictor effect.

Oxymetazoline causes vasoconstriction of the mucous membranes of the nose, paranasal sinuses and the Eustachian tube, which leads to a decrease in their edema and the release of nasal breathing in allergic and / or infectious-inflammatory rhinitis (rhinitis).

Due to the presence in the composition of the drug of excipients (microcrystalline cellulose and carmellose sodium and povidone-K29-32) Afrin® moisturizing nasal spray does not flow out of the nose and does not flow down the throat, since after being introduced into the nasal passages, the spray becomes more viscous and retains more effective on nasal mucous membranes than standard aqueous solution.

This drug contains moisturizers (glycerol and macrogol-1450) to help retain moisture, which helps keep dry or irritated nasal mucosa moisturized.

According to clinical studies, the drug begins to act within 1 minute and lasts up to 12 hours.

Pharmacokinetics

When used as a nasal spray, oxymetazoline is practically not detected in blood plasma.

Side effects

In general, the drug is well tolerated, and possible adverse events are usually mild and transient.

Transient dryness and burning of the nasal mucosa, dry mouth and throat, sneezing

increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disturbances.

With prolonged use - tachyphylaxis, reactive hyperemia and atrophy of the nasal mucosa.

Benzalkonium chloride, which is part of the drug, can cause local skin reactions.

Selling features

Available without a prescription

Special conditions

With prolonged use (more than one week), the symptoms of nasal congestion may recur.

If it is necessary to continue treatment for more than 5 days, a consultation with a doctor is required.

Avoid getting the drug in the eyes.

The drug, when used correctly and in recommended doses, does not affect driving vehicles and working with mechanisms, however, if side effects such as dizziness occur, you should refrain from these activities.

Application during pregnancy and lactation

The safety of the drug in pregnant women and during lactation has not been established, therefore, the drug should be prescribed to pregnant or breastfeeding women only on the recommendation of a doctor if the expected benefit from using the drug for the mother outweighs the potential risk to the fetus or infant.

Indications

Difficulty in nasal breathing with colds, sinus inflammation, eustachitis, hay fever, allergic rhinitis, congestion and conjunctival edema

Contraindications

Hypersensitivity to sympathomimetic drugs, to any component of the drug, atrophic rhinitis, simultaneous use of monoamine oxidase inhibitors (including a period of 14 days after their cancellation), children under 6 years of age.

Carefully

Coronary artery disease, arrhythmias, chronic cardiac weeks

Name ENG

AFRIN MOISTURIZING

Clinical and pharmacological group

A vasoconstrictor drug for local use in ENT practice

ATX code

Oxymetazoline

Dosage

0.05% x 15ml

Structure

Active ingredient: oxymetazoline hydrochloride 0.5 mg.

Excipients: microcrystalline cellulose and sodium carmellose (Avicel RC-591) 30 mg, sodium hydrogen phosphate 0.975 mg, sodium dihydrogen phosphate monohydrate 5.525 mg, disodium edetate dihydrate 0.3 mg, macrogol-1450 50 mg, povidone-K29-32 30 mg, benzyl alcohol 2.5 mg, lemon flavor 1.5 mg, benzalkonium chloride solution 17% 1.471 mg, glycerol 5 mg, purified water qs up to 1 ml.

Indications

Symptomatic therapy of rhinitis (rhinitis) of allergic and / or infectious-inflammatory etiology

sinusitis

eustachitis

hay fever.

INN / Active ingredient

Oxymetazoline

Contraindications

Atrophic rhinitis

simultaneous use of MAO inhibitors (including a period of 14 days after their cancellation)

children under 6 years of age.

hypersensitivity to drug components

hypersensitivity to sympathomimetic drugs.,

With care: coronary artery disease, arrhythmias, chronic heart failure, severe atherosclerosis, arterial hypertension, hyperthyroidism, diabetes mellitus, chronic renal failure, angle-closure glaucoma, prostatic hyperplasia with clinical symptoms, pregnancy, lactation.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2 years

Specifications