algeldrat, magnesium hydroxide | Almagel suspension 170 ml
Special Price
$17.64
Regular Price
$25.00
In stock
SKU
BID461859
Latin name
ALMAGELВ®
ALMAGELВ®
Latin name
ALMAGELВ®
Release form
Suspension for oral administration.
Packaging
Bottle 170 ml.
Pharmacological action
Pharmacotherapeutic group
Antacid
ATX code: A02AX
Pharmacological action
Pharmacodynamics
Almagel® is a drug that is a balanced combination of aluminum hydroxide and aluminum hydroxide. It neutralizes free hydrochloric acid in the stomach, reduces the activity of pepsin, which leads to a decrease in the digesting activity of gastric juice. It has an enveloping, adsorbing effect. Protects the gastric mucosa by stimulating the synthesis of prostaglandins (cytoprotective effect). This protects the mucous membrane from inflammatory and erosive hemorrhagic lesions as a result of the use of irritating and ulcerogenic agents, such as ethyl alcohol and non-steroidal anti-inflammatory drugs (e.g. indomethacin, diclofenac, aspirin, acetylsalicylic acid, corticosteroid drugs). The therapeutic effect after taking the drug occurs in 3-5 minutes. The duration of action depends on the rate of gastric emptying. When taken on an empty stomach, the action lasts up to 60 minutes. When taken an hour after a meal, the antacid effect can last up to 3 hours. Does not cause secondary hypersecretion of gastric juice.
Pharmacokinetics
Algeldrat
Absorption - small amounts of the drug are absorbed, which practically do not change the concentration of aluminum salts in the blood.
Distribution - no.
Metabolism - no.
Excretion - excreted through the intestines.
Magnesium hydroxide
Absorption - magnesium ions are resorbed in about 10% of the dose and do not change the concentration of magnesium ions in the blood.
Distribution - usually locally.
Metabolism - no. Excretion - excreted through the intestines.
Indications
Treatment of
Acute gastritis, chronic gastritis with increased and normal secretory function of the stomach (in the acute phase) acute duodenitis, enteritis, colitis
gastric ulcer and duodenal ulcer (in the exacerbation phase) gastropharyngeal reflux, Esophagitis duodenogastric reflux
symptomatic gastrointestinal ulcers of various genesis of erosion of the mucous membrane of the upper gastrointestinal tract
acute pancreatitis, exacerbation of chronic pancreatitis
heartburn and epigastric pain after errors in nutrition, excessive use of mucous drug ethanol, excessive use of ethanol, mucous drugs, ethanol the stomach.
Prevention of gastric and duodenal disorders
reduction of irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.
Contraindications
Hypersensitivity to the active or to any auxiliary substance that is part of the drug.
Severe renal failure (due to the danger of developing hypermagnesemia and aluminum intoxication).
Pregnancy.
Alzheimer's disease.
Hypophosphatemia.
Children under 10 years old.
Congenital intolerance to fructose (contains sorbitol)
Pregnancy and lactation
Animal studies have shown that there is no evidence of teratogenic potential or other adverse effects on the embryo and / or fetus.
There is no clinical data on the use of Almagel in pregnant women. The drug is not recommended during pregnancy, but if the intended benefit of its use exceeds the potential risk to the fetus, the drug should be taken under medical supervision for no more than 5-6 days.
There is no data on the release of the active substances of the drug with breast milk. Almagel can be used during breastfeeding only after a careful assessment of the ratio of benefits for the mother and the potential risk for the newborn.
During breastfeeding, it is recommended to use no more than 5-6 days under the supervision of a doctor.
Composition
5 ml (one scoop) suspensions contain:
Active ingredients:
Aluminum hydroxide gel -2.18 g
in terms of Al2O3 -218 mg
Magnesium hydroxide infusion - 350 mg in
- 75 mg in mg
Excipients:
Hydrogen peroxide solution 30% - 0.41 mg, sorbitol - 801.15 mg, hyetellose - 10.90 mg, methyl parahydroxybenzoate - 10.90 mg, propyl parahydroxybenzoate - 1.333 mg, butyl parahydroxybenzoate - 1.3 sodium 0.818 mg, propylene glycol - 327.00 mg, macrogol 4000 - 218.00 mg, lemon oil - 1.635 mg, ethanol 96% - 98.10 mg, and purified to 5 ml
Dosage and administration of
Treatment of
Adults and children over 15 years of age
5-10 ml (1-2 scoops) or 1 sachet 3-4 times a day.
If necessary, a single dose can be increased to 15 ml (3 scoops).
For children from 10 to 15 years old
Apply at a dose equal to half the dose for adults - 1 scoop 2-4 times a day or 2 scoops 1-2 times a day or 1 sachet 1-2 times a day.
The drug is taken 45-60 minutes after eating and in the evening before bedtime.
After achieving the therapeutic effect, the daily dose is reduced to 5 ml (1 scoop) 3-4 times a day or 1 sachet 1-2 times a day for 15-20 days.
It is not recommended to take fluids within 15 minutes after taking the drug Almagel.
Before use, the suspension must be thoroughly homogenized by shaking the bottle or kneading and shaking the bag.
For the prevention of
5-15 ml (1-3 scoops) or 1 sachet 15 minutes before taking drugs with an irritating effect.
Side effects
Almagel can cause constipation, which disappears after a dose reduction.
In rare cases, nausea, vomiting, stomach spasm, changes in taste, allergic reactions and hypermagnesemia (increased levels of magnesium in the blood) are observed. With prolonged use of the drug in patients with renal failure and dialysis, changes in mood and mental activity are possible. With prolonged use of high doses of the drug, along with a deficiency of phosphorus in food, osteomalacia may occur.
Drug Interaction
May absorb some drugs, thus reducing their absorption, so while taking other medicines, they should be taken 1-2 hours before or after taking Almagel.
Almagel reduces the acidity of gastric juice, and it can affect the effect of a large number of medicines at the same time.
Almagel reduces the effect of histamine H2 receptor blockers (cimetidine, ranitidine, famotidine), cardiac glycosides, iron salts, lithium preparations, quinidine, mexiletine, phenothiazine preparations, tetracycline taconazine, ciprofloxazone, ciprofonazole, ciprofonazole
At the same time intake of intestinal preparations the raised pH of gastric juice can lead to the accelerated disturbance of the yus membrane and cause irritation of the stomach and duodenum. Almagel may affect the results of some laboratory and functional tests and tests: it reduces the level of gastric secretion in determining its acidity, changes the results of tests using technetium (TC ), such as bone scintigraphy and some tests for esophageal examination, raises the serum phosphorus, serum pH and urine values.
Overdose
With a single overdose, there are no signs of overdose other than constipation, flatulence, a metallic taste in the mouth.
At long reception of high doses formation of stones in kidneys, occurrence of heavy constipation, easy drowsiness, hypermagnesemia is possible. Signs of metabolic alkalosis can also be observed: mood or mental activity change, numbness or muscle pain, irritability and rapid fatigue, slowing of breathing, unpleasant taste sensations.
In these cases, it is necessary to take immediate steps to quickly remove the drug from the body - gastric lavage, vomiting, activated charcoal.
Storage conditions
The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25 РC. Do not freeze.
Expiration
2 years.
pharmacy leave terms without a prescription
Dosage form
Dosage form
suspension for oral administration
ALMAGELВ®
Release form
Suspension for oral administration.
Packaging
Bottle 170 ml.
Pharmacological action
Pharmacotherapeutic group
Antacid
ATX code: A02AX
Pharmacological action
Pharmacodynamics
Almagel® is a drug that is a balanced combination of aluminum hydroxide and aluminum hydroxide. It neutralizes free hydrochloric acid in the stomach, reduces the activity of pepsin, which leads to a decrease in the digesting activity of gastric juice. It has an enveloping, adsorbing effect. Protects the gastric mucosa by stimulating the synthesis of prostaglandins (cytoprotective effect). This protects the mucous membrane from inflammatory and erosive hemorrhagic lesions as a result of the use of irritating and ulcerogenic agents, such as ethyl alcohol and non-steroidal anti-inflammatory drugs (e.g. indomethacin, diclofenac, aspirin, acetylsalicylic acid, corticosteroid drugs). The therapeutic effect after taking the drug occurs in 3-5 minutes. The duration of action depends on the rate of gastric emptying. When taken on an empty stomach, the action lasts up to 60 minutes. When taken an hour after a meal, the antacid effect can last up to 3 hours. Does not cause secondary hypersecretion of gastric juice.
Pharmacokinetics
Algeldrat
Absorption - small amounts of the drug are absorbed, which practically do not change the concentration of aluminum salts in the blood.
Distribution - no.
Metabolism - no.
Excretion - excreted through the intestines.
Magnesium hydroxide
Absorption - magnesium ions are resorbed in about 10% of the dose and do not change the concentration of magnesium ions in the blood.
Distribution - usually locally.
Metabolism - no. Excretion - excreted through the intestines.
Indications
Treatment of
Acute gastritis, chronic gastritis with increased and normal secretory function of the stomach (in the acute phase) acute duodenitis, enteritis, colitis
gastric ulcer and duodenal ulcer (in the exacerbation phase) gastropharyngeal reflux, Esophagitis duodenogastric reflux
symptomatic gastrointestinal ulcers of various genesis of erosion of the mucous membrane of the upper gastrointestinal tract
acute pancreatitis, exacerbation of chronic pancreatitis
heartburn and epigastric pain after errors in nutrition, excessive use of mucous drug ethanol, excessive use of ethanol, mucous drugs, ethanol the stomach.
Prevention of gastric and duodenal disorders
reduction of irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.
Contraindications
Hypersensitivity to the active or to any auxiliary substance that is part of the drug.
Severe renal failure (due to the danger of developing hypermagnesemia and aluminum intoxication).
Pregnancy.
Alzheimer's disease.
Hypophosphatemia.
Children under 10 years old.
Congenital intolerance to fructose (contains sorbitol)
Pregnancy and lactation
Animal studies have shown that there is no evidence of teratogenic potential or other adverse effects on the embryo and / or fetus.
There is no clinical data on the use of Almagel in pregnant women. The drug is not recommended during pregnancy, but if the intended benefit of its use exceeds the potential risk to the fetus, the drug should be taken under medical supervision for no more than 5-6 days.
There is no data on the release of the active substances of the drug with breast milk. Almagel can be used during breastfeeding only after a careful assessment of the ratio of benefits for the mother and the potential risk for the newborn.
During breastfeeding, it is recommended to use no more than 5-6 days under the supervision of a doctor.
Composition
5 ml (one scoop) suspensions contain:
Active ingredients:
Aluminum hydroxide gel -2.18 g
in terms of Al2O3 -218 mg
Magnesium hydroxide infusion - 350 mg in
- 75 mg in mg
Excipients:
Hydrogen peroxide solution 30% - 0.41 mg, sorbitol - 801.15 mg, hyetellose - 10.90 mg, methyl parahydroxybenzoate - 10.90 mg, propyl parahydroxybenzoate - 1.333 mg, butyl parahydroxybenzoate - 1.3 sodium 0.818 mg, propylene glycol - 327.00 mg, macrogol 4000 - 218.00 mg, lemon oil - 1.635 mg, ethanol 96% - 98.10 mg, and purified to 5 ml
Dosage and administration of
Treatment of
Adults and children over 15 years of age
5-10 ml (1-2 scoops) or 1 sachet 3-4 times a day.
If necessary, a single dose can be increased to 15 ml (3 scoops).
For children from 10 to 15 years old
Apply at a dose equal to half the dose for adults - 1 scoop 2-4 times a day or 2 scoops 1-2 times a day or 1 sachet 1-2 times a day.
The drug is taken 45-60 minutes after eating and in the evening before bedtime.
After achieving the therapeutic effect, the daily dose is reduced to 5 ml (1 scoop) 3-4 times a day or 1 sachet 1-2 times a day for 15-20 days.
It is not recommended to take fluids within 15 minutes after taking the drug Almagel.
Before use, the suspension must be thoroughly homogenized by shaking the bottle or kneading and shaking the bag.
For the prevention of
5-15 ml (1-3 scoops) or 1 sachet 15 minutes before taking drugs with an irritating effect.
Side effects
Almagel can cause constipation, which disappears after a dose reduction.
In rare cases, nausea, vomiting, stomach spasm, changes in taste, allergic reactions and hypermagnesemia (increased levels of magnesium in the blood) are observed. With prolonged use of the drug in patients with renal failure and dialysis, changes in mood and mental activity are possible. With prolonged use of high doses of the drug, along with a deficiency of phosphorus in food, osteomalacia may occur.
Drug Interaction
May absorb some drugs, thus reducing their absorption, so while taking other medicines, they should be taken 1-2 hours before or after taking Almagel.
Almagel reduces the acidity of gastric juice, and it can affect the effect of a large number of medicines at the same time.
Almagel reduces the effect of histamine H2 receptor blockers (cimetidine, ranitidine, famotidine), cardiac glycosides, iron salts, lithium preparations, quinidine, mexiletine, phenothiazine preparations, tetracycline taconazine, ciprofloxazone, ciprofonazole, ciprofonazole
At the same time intake of intestinal preparations the raised pH of gastric juice can lead to the accelerated disturbance of the yus membrane and cause irritation of the stomach and duodenum. Almagel may affect the results of some laboratory and functional tests and tests: it reduces the level of gastric secretion in determining its acidity, changes the results of tests using technetium (TC ), such as bone scintigraphy and some tests for esophageal examination, raises the serum phosphorus, serum pH and urine values.
Overdose
With a single overdose, there are no signs of overdose other than constipation, flatulence, a metallic taste in the mouth.
At long reception of high doses formation of stones in kidneys, occurrence of heavy constipation, easy drowsiness, hypermagnesemia is possible. Signs of metabolic alkalosis can also be observed: mood or mental activity change, numbness or muscle pain, irritability and rapid fatigue, slowing of breathing, unpleasant taste sensations.
In these cases, it is necessary to take immediate steps to quickly remove the drug from the body - gastric lavage, vomiting, activated charcoal.
Storage conditions
The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25 РC. Do not freeze.
Expiration
2 years.
pharmacy leave terms without a prescription
Dosage form
Dosage form
suspension for oral administration
Write Your Own Review