Clotrimazolum | Candide vaginal tablets 500 mg, 1 mg.

Packing

1 pc

Pharmacological action

Candide - a wide spectrum antifungal.

The antimycotic effect of the active substance, clotrimazole (an imidazole derivative), is associated with impaired synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.

It acts fungistatically in small concentrations, fungicidal in large concentrations, and not only on proliferating cells.

In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, As a result, there is an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.

Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of colorful lichen (Pityriasis versicolor) and the pathogen of erythrasma.

It has antimicrobial activity against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

Indications of

genital infections caused by yeast-like fungi of the genus Candida and / or Trichomonas vaginalis (candidiasis vulvovaginitis, trichomoniasis)

genital superinfection caused by microorganisms sensitive to clotrimazolumiduration sordl.

Contraindications

hypersensitivity to clotrimazole or

excipients I trimester of pregnancy

menstruation period.

Precautions: period of breastfeeding.

Composition

Tablets vaginal

1 tablet contains:

Active substance:

Clotrimazole 500 mg

Excipients:

Lactose

Starch

carboxymethyl starch sodium

Talc purified

Magnesium stearate

Silicon dioxide colloid

Methyl parahydroxybenzoate (methyl paraben)

Propyl (propylparaben)

Dosage and Administration

Topically. It is administered intravaginally, deeply, in the supine position with slightly bent legs.

500 mg once daily (in the evening). A second course of treatment is possible after consulting a doctor.

For the rehabilitation of the birth canal, a single administration of 1 tablet is recommended.

Side effects

Itching, burning and swelling of the vaginal mucosa, vaginal discharge, headache, gastralgia, rapid urination, intercurrent cystitis, burning sensation in the penis of the sexual partner, pain during intercourse.

Overdose

The use of the drug in elevated doses does not cause any reactions and conditions that are life-threatening.

Symptoms (in case of unintended use of the drug by mouth): anorexia, nausea, vomiting, gastralgia, impaired liver function rarely - drowsiness, hallucinations, pollakiuria, skin allergic reactions.

Treatment: the appointment of activated carbon, if necessary - symptomatic therapy there is no specific antidote.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 РC.

Expiration

4 years.

Dispensing conditions from

pharmacies No prescription

Form of Treatment

tablets vaginalyn e

Indications

From thrush, From inflammation of the female genital organs

Possible product names

CANDID 0.5 N1 TAG VAG / WITH APPLICATOR /

Candid 500mg Tab. vaginal (with applicator) X1 (R)

CANDID TAB. VAGIN. WITH APPLICATOR 500MG No. 1

Candide vaginal tablets 500 mg 1 pc.

Candide vaginal tablets 500 mg, 1 pc.

Glenmark Pharmaceuticals Ltd., India