Co-trimoxazole sulfamethoxazole, trimethoprim | Biseptol suspension 240 mg / 5 ml, 80 ml
Special Price
$15.68
Regular Price
$23.00
In stock
SKU
BID473151
Latin name
BISEPTOL
BISEPTOL
Latin name
BISEPTOL
Release form
Suspension for oral administration.
Packing
Bottle of 80 ml.
Pharmacological action
Biseptol is a combined antibacterial drug with a wide spectrum of bactericidal action, the mechanism of which is due to the blocking of folate biosynthesis in microbial cells.
Sulfamethoxazole disrupts the synthesis of dihydrofolate, and trimethoprim prevents the conversion of dihydrofolate to tetrahydrofolate.
Active against almost all groups of microorganisms - gram-negative bacteria: Salmonella spp., Shigella spp., Neisseria spp., Proteus vulgaris, Vibrio cholerae, Yersinia spp., Escherichia coli, Corynebacterium spp. Gram-positive bacteria: Staphylococcus spp. and others.
Chlamydia spp., Actinomyces spp., Klebsiella spp. are also sensitive to the drug.
Mycobacteria, viruses, and most anaerobic bacteria are resistant to the drug.
Indications
Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to the drug: - respiratory tract infections (including bronchitis, pneumonia, lung abscess, pleural empyema)
- otitis media, sinusitis
- meningitis, brain abscess
- infections of the genitourinary system (including pyelonephritis, urethritis, salpingitis, prostatitis)
- gonorrhea
- gastrointestinal tract infections (including typhoid fever, paratyphoid, bacterial dysentery, cholera, diarrhea).
Contraindications
- severe hepatic impairment
- severe renal impairment (CC less than 15 ml / min)
- disorders of the hematopoietic system
- severe cardiovascular disease
- glucose-6-phosphate deficiency - children's age up to 3 months
- hypersensitivity to the components of the drug.
Special instructions
Caution must be exercised when prescribing Biseptolum to patients with impaired liver and / or kidney function, with a history of allergic reactions, with folic acid deficiency, to elderly patients.
The appearance of a skin rash or severe diarrhea is an indication for drug withdrawal.
Biseptol is not indicated for the treatment of angina caused by streptococcus.
During treatment with Biseptolum, adequate fluid intake should be ensured due to the risk of crystalluria and urolithiasis.
When determining creatinine levels using Jaffe alkaline picrinate while taking Biseptol, it should be borne in mind that the result can be 10% higher than true.
Monitoring laboratory parameters
With prolonged use of the drug, it is necessary to control the picture of peripheral blood.
Composition
5 ml contains:
Active ingredients: sulfamethoxazole 200 mg trimethoprim 40 mg
Excipients: macrogol glyceryl hydroxide stearate, magnesium aluminum silicate, sodium carmellose, citric acid hydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxy hydroxyhydroxy , propylene glycol, purified water.
Dosage and administration
The drug is prescribed at a dose of 6 mg trimethoprim and 30 mg sulfamethoxazole per 1 kg of body weight / day.
Children from 3 to 6 months old - 2.5 ml every 12 hours
children from 7 months to 3 years old - 2.5-5 ml every 12 hours
children from 4 to 6 years old - 5-10 ml every 12 hours
children from 7 to 12 years old - 10 ml every 12 hours
adults and children over 12 years old - 20 ml every 12 hours
Duration of therapy - 10-14 days (with shigellosis - 5 days).
For infections caused by Pneumocystis carinii, the dose is 120 mg / kg body weight per day, the drug is taken every 6 hours for 14-21 days.
When prescribing the drug to patients with impaired renal function (CC 15-30 ml / min), the dose should be reduced by half.
Side effects of the
From the digestive system: rarely - nausea, vomiting, diarrhea in isolated cases - pseudomembranous colitis, cholestatic hepatitis.
Allergic reactions: in isolated cases - Stevens-Johnson syndrome, Lyell's syndrome.
From the hemopoietic system: in isolated cases - reversible thrombocytopenia, leukopenia, neutropenia, agranulocytosis, megaloblastic anemia.
From the urinary system: rarely - hematuria, nephritis.
From the side of the central nervous system: in isolated cases - headache, depression, dizziness.
Side effects are usually mild and reversible after discontinuation of the drug.
Overdose
Symptoms: nausea, vomiting, clouding of consciousness.
Treatment: withdrawal of the drug, gastric lavage (not later than 2 h after drug administration), copious drink, forced diuresis, folinate calcium intake (5-10 mg / day).
Storage Conditions
Store in a dry, dark place and out of the reach of children.
lekarstvennaja form
suspensions for pryema inside
Prescription
Children over 2 months old, Children prescribed by a doctor
Indications
Indications
Salmonellosis, Otitis, Infectious diseases, Pr prostatitis, pneumonia, Boils, urethritis, bronchitis
Medan Farm, Poland
BISEPTOL
Release form
Suspension for oral administration.
Packing
Bottle of 80 ml.
Pharmacological action
Biseptol is a combined antibacterial drug with a wide spectrum of bactericidal action, the mechanism of which is due to the blocking of folate biosynthesis in microbial cells.
Sulfamethoxazole disrupts the synthesis of dihydrofolate, and trimethoprim prevents the conversion of dihydrofolate to tetrahydrofolate.
Active against almost all groups of microorganisms - gram-negative bacteria: Salmonella spp., Shigella spp., Neisseria spp., Proteus vulgaris, Vibrio cholerae, Yersinia spp., Escherichia coli, Corynebacterium spp. Gram-positive bacteria: Staphylococcus spp. and others.
Chlamydia spp., Actinomyces spp., Klebsiella spp. are also sensitive to the drug.
Mycobacteria, viruses, and most anaerobic bacteria are resistant to the drug.
Indications
Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to the drug: - respiratory tract infections (including bronchitis, pneumonia, lung abscess, pleural empyema)
- otitis media, sinusitis
- meningitis, brain abscess
- infections of the genitourinary system (including pyelonephritis, urethritis, salpingitis, prostatitis)
- gonorrhea
- gastrointestinal tract infections (including typhoid fever, paratyphoid, bacterial dysentery, cholera, diarrhea).
Contraindications
- severe hepatic impairment
- severe renal impairment (CC less than 15 ml / min)
- disorders of the hematopoietic system
- severe cardiovascular disease
- glucose-6-phosphate deficiency - children's age up to 3 months
- hypersensitivity to the components of the drug.
Special instructions
Caution must be exercised when prescribing Biseptolum to patients with impaired liver and / or kidney function, with a history of allergic reactions, with folic acid deficiency, to elderly patients.
The appearance of a skin rash or severe diarrhea is an indication for drug withdrawal.
Biseptol is not indicated for the treatment of angina caused by streptococcus.
During treatment with Biseptolum, adequate fluid intake should be ensured due to the risk of crystalluria and urolithiasis.
When determining creatinine levels using Jaffe alkaline picrinate while taking Biseptol, it should be borne in mind that the result can be 10% higher than true.
Monitoring laboratory parameters
With prolonged use of the drug, it is necessary to control the picture of peripheral blood.
Composition
5 ml contains:
Active ingredients: sulfamethoxazole 200 mg trimethoprim 40 mg
Excipients: macrogol glyceryl hydroxide stearate, magnesium aluminum silicate, sodium carmellose, citric acid hydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxyhydroxy hydroxyhydroxy , propylene glycol, purified water.
Dosage and administration
The drug is prescribed at a dose of 6 mg trimethoprim and 30 mg sulfamethoxazole per 1 kg of body weight / day.
Children from 3 to 6 months old - 2.5 ml every 12 hours
children from 7 months to 3 years old - 2.5-5 ml every 12 hours
children from 4 to 6 years old - 5-10 ml every 12 hours
children from 7 to 12 years old - 10 ml every 12 hours
adults and children over 12 years old - 20 ml every 12 hours
Duration of therapy - 10-14 days (with shigellosis - 5 days).
For infections caused by Pneumocystis carinii, the dose is 120 mg / kg body weight per day, the drug is taken every 6 hours for 14-21 days.
When prescribing the drug to patients with impaired renal function (CC 15-30 ml / min), the dose should be reduced by half.
Side effects of the
From the digestive system: rarely - nausea, vomiting, diarrhea in isolated cases - pseudomembranous colitis, cholestatic hepatitis.
Allergic reactions: in isolated cases - Stevens-Johnson syndrome, Lyell's syndrome.
From the hemopoietic system: in isolated cases - reversible thrombocytopenia, leukopenia, neutropenia, agranulocytosis, megaloblastic anemia.
From the urinary system: rarely - hematuria, nephritis.
From the side of the central nervous system: in isolated cases - headache, depression, dizziness.
Side effects are usually mild and reversible after discontinuation of the drug.
Overdose
Symptoms: nausea, vomiting, clouding of consciousness.
Treatment: withdrawal of the drug, gastric lavage (not later than 2 h after drug administration), copious drink, forced diuresis, folinate calcium intake (5-10 mg / day).
Storage Conditions
Store in a dry, dark place and out of the reach of children.
lekarstvennaja form
suspensions for pryema inside
Prescription
Children over 2 months old, Children prescribed by a doctor
Indications
Indications
Salmonellosis, Otitis, Infectious diseases, Pr prostatitis, pneumonia, Boils, urethritis, bronchitis
Medan Farm, Poland
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