Contractubex gel, 50 g

• Hypertrophic and keloid scars after surgery, amputation, burns and trauma

• Ankylosis (contractures) of the joints

• Dupuytren's contracture

• Traumatic tendon contractures

• Stretch marks after pregnancy

• Atrophic scars (particularly after acne or furunculosis)

• Prevention of the formation of pathological scars in the postoperative period or after an accident Can be used in children.

Outwardly.
The consumption of the drug in one application is an average of 0.5 cm of gel on a scar surface with an area of ??20-25 cm2. For adults, the drug is applied 2-3 times a day, for children over 1 year old, the drug is applied 1-2 times a day. The gel is applied in a thin layer and lightly rubbed into the scar tissue. The course of treatment for fresh scars (including ankylosis (contractures) of the joints, traumatic tendon contractures, stretch marks after pregnancy) averages 4 weeks. With old dense scars (including ankylosis (contractures) of the joints, traumatic tendon contractures, stretch marks after pregnancy), an occlusive dressing with a gel is applied at night. The course of treatment is on average 3-6 months. With Dupuytren's contracture, the course of treatment is 12 months on average. For prevention, use the phase after the epithelialization of the wound (not applied to granulation).

per 100 g of gel
Active substances:
Liquid onion bulb extract 10 g
Sodium heparin 0.04 g (5000 ME)
Allantoin 1 g
Excipients: Sorbic
acid 0.1 g
Methyl parahydroxybenzoate 0.15 g
Xanthan gum (xantural 75) 2 g
Macrogol 200 (Polyethylene glycol 200) 25 g
Flavored oil (aroma 231616) 0.3 g
Purified water 61.41 g

Hypersensitivity to the components of the drug, pregnancy, breastfeeding period, children under 1 year of age.

Tradename:

Contractubex

Dosage form:

gel for external use

Description

gel from light yellow to light brown in color with a characteristic odor.

Composition: per 100 g of gel
Active substances:
Liquid onion bulb extract 10 g
Sodium heparin 0.04 g (5000 ME)
Allantoin 1 g
Excipients: Sorbic
acid 0.1 g
Methyl parahydroxybenzoate 0.15 g
Xanthan gum (xantural 75) 2 g
Macrogol 200 (Polyethylene glycol 200) 25 g
Flavored oil (aroma 231616) 0.3 g
Purified water 61.41 g

Pharmacotherapeutic group:

D03AX. Hyper-scarring is a remedy.

Pharmacological properties

Pharmacodynamics:
Combined drug, the action of which is due to the properties of its constituent components. It has fibrinolytic anti-inflammatory (due to the presence of Serae extract), antithrombotic (due to the presence of heparin) and keratolytic (due to the presence of allantoin) action. Stimulates cell regeneration without hyperplasia. Inhibits the proliferation of keloid fibroblasts.

Pharmacokinetics:
It was shown experimentally that heparin penetrates into the connective tissue of the dermis in a clinically sufficient amount within 4 hours. Deep penetration is provided by the combination of heparin with Serae bulb extract and allantoin (transepidermal heparinization).
When using the drug Contractubex, systemic absorption is not observed.

Indications for use

• Hypertrophic and keloid scars after surgery, amputation, burns and trauma

• Ankylosis (contractures) of the joints

• Dupuytren's contracture

• Traumatic tendon contractures

• Stretch marks after pregnancy

• Atrophic scars (particularly after acne or furunculosis)

• Prevention of the formation of pathological scars in the postoperative period or after an accident Can be used in children.

Contraindications

Hypersensitivity to the components of the drug, pregnancy, breastfeeding period, children under 1 year of age.

Method of administration and dosage

Outwardly.
The consumption of the drug in one application is an average of 0.5 cm of gel on a scar surface with an area of ??20-25 cm2. For adults, the drug is applied 2-3 times a day, for children over 1 year old, the drug is applied 1-2 times a day. The gel is applied in a thin layer and lightly rubbed into the scar tissue. The course of treatment for fresh scars (including ankylosis (contractures) of the joints, traumatic tendon contractures, stretch marks after pregnancy) averages 4 weeks. With old dense scars (including ankylosis (contractures) of the joints, traumatic tendon contractures, stretch marks after pregnancy), an occlusive dressing with a gel is applied at night. The course of treatment is on average 3-6 months. With Dupuytren's contracture, the course of treatment is 12 months on average. For prevention, use the phase after the epithelialization of the wound (not applied to granulation).

Side effect

Usually Contractubex is very well tolerated, even with prolonged use. Most often, skin reactions were noted at the site of application.
Classification of the frequency of occurrence of adverse reactions: very often (? 1/10). ? common (1/100 to part of the skin: frequent: pruritus, erythema, telangiectasia, atrophy of the rumen; rare:. hyperpigmentation of the skin, skin atrophy
has also been reported following spontaneous adverse reactions:
Infectious diseases: the frequency has not been established: pustular rash.
With the immune system: the frequency is not installed: hypersensitivity (allergic reactions).
From the nervous system: the frequency is not installed: paresthesia.
For the skin:frequency not established: urticaria, rash, pruritus, erythema, skin irritation, papules, burning sensation, feeling of tension, contact dermatitis.
General disorders and disorders at the site of application: frequency not established: edema, pain and peeling at the site of application. Itching, which is a natural manifestation of scar formation, usually does not require discontinuation of the drug.
If any of the side effects indicated in the instructions are aggravated, or any other side effects not indicated in the instructions are noted, you should immediately inform your doctor.

Interaction with other medicinal products

Not described.

Overdose

Not described.

special instructions

To enhance the effect of the drug, apply to previously steamed skin. It can be used in combination with physiotherapy. When treating fresh scars, avoid ultraviolet radiation, exposure to cold and intense massage.
The effect of the drug during pregnancy, during breastfeeding and in children under 1 year of age has not been studied.

Influence on the ability to drive vehicles, mechanisms

Does not affect.

Release form

Gel for external use, 20 or 50 g in an aluminum tube. The tube together with the instructions for use is placed in a cardboard box.

Storage conditions

At a temperature not exceeding 25 ? — in a dry place. Keep out of the reach of children.

Shelf life

3 years.
6 months from the date of opening the tube. Do not use after the expiration date.

Conditions of dispensing from pharmacies

Without recipe.