Corilip-neo suppositories, No. 10

With prophylactic and therapeutic purposes in complex therapy for various pathological conditions in children, such as:

-chronic tissue hypoxia;

-decreased immunity;

-bacterial and viral infections, incl. acute intestinal infections;

-chronic somatic diseases;

-chronic intoxication;

- malnutrition (malnutrition) in children.

Rectally. Having freed from the packaging, insert the suppository into the anus after preliminary emptying of the intestines.

Suppositories are prescribed for children under 1 year of age, 1 supp. / Day.

The duration of the course of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 months).

Rectal suppositories

1 supp.

active substance:

cocarboxylase hydrochloride (cocarboxylase) 12.5 mg

riboflavin 1 mg

lipoic acid (thioctic acid) 6 mg

excipients: solid fat (fatty acids glycerides) - 930.5 mg

• Hypersensitivity reaction to the components that make up the drug;

• inflammation or bleeding in the rectum (contraindication associated with the route of administration).

pharmachologic effect

Combined preparation, the action of which is determined by the effects of its constituent vitamins and coenzymes, as well as their synergistic action.

Cocarboxylase (coenzyme) catalyzes carboxylation and decarboxylation of ?-keto acids and participates in carbohydrate metabolism. Through participation in the pentose cycle, it indirectly regulates the synthesis of nucleic acids, proteins, lipids. Promotes the correction of metabolic acidosis and cellular hypoxia, as well as other metabolic disorders (failure of liver, kidney, cardiovascular system, chronic intoxication).

Riboflavin (vitamin B2) as a coenzyme of flavin proteins is involved in the regulation of redox reactions (in the processes of carbohydrate, protein and fat metabolism). Plays an important role in the synthesis of hemoglobin and in maintaining normal visual function of the eye, the state of the mucous membranes and skin.

Thioctic acid is involved in the oxidative decarboxylation of pyruvic acid and other ?-keto acids, in the regulation of lipid and carbohydrate metabolism, and plays an important role in the formation of energy in the body. Thioctic acid has a hepatoprotective effect, improves the detoxification function of the liver, protects against the effects of exo- and endotoxins.

Corilip improves tissue metabolism in various physiological and pathological conditions that require correction with cofactors and substrates.

Side effect

Allergic reactions are possible - urticaria, itching, bronchospasm, dyspeptic symptoms.

If any adverse reactions occur, stop using the drug and consult a doctor.

Application in children

Application is possible according to the dosage regimen.

special instructions

The criteria for the duration of treatment, along with the clinical state, are the cytochemical parameters of the activity of enzymes of peripheral blood leukocytes (succinate dehydrogenase and glycerophosphate dehydrogenase).

Overdose

Overdose cases are not described.

Drug interactions

No negative interaction was noted. The drug can be used in combination therapy.