Cycloferon tablets 150mg, No. 20

In adults (as part of complex therapy)

-influenza and acute respiratory diseases;

- herpetic infection.

In children in complex therapy, starting from 4 years

-influenza and acute respiratory diseases;

- herpetic infection.

In children from 4 years of age, for the prevention of influenza and acute respiratory diseases.

Inside, 1 time per day 30 minutes before meals, without chewing, drinking 1/2 glass of water.

Children: 4-6 years old - 150 mg (1 tab.) Per appointment; 7Ц11 years old - 300Ц450 mg (2Ц3 tablets) per appointment.

Adults and children over 12 years old: 450-600 mg (3-4 tablets) per appointment.

It is advisable to repeat the course 2-3 weeks after the end of the first course.

Adults

In the treatment of influenza and acute respiratory infections, the drug is taken on the 1st, 2nd, 4th, 6th, 8th day (course of treatment - 20 tablets). Treatment should be started at the first symptoms of the disease. With a severe course of influenza, 6 tablets are taken on the first day. If necessary, symptomatic therapy is additionally carried out (antipyretic, analgesic, expectorant drugs).

In case of herpes infection, the drug is taken on 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days (course of treatment - 40 tablets). Treatment is most effective when the first symptoms of the disease appear.

Children from 4 years of age

In case of influenza and acute respiratory diseases, the drug is taken in age doses on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20, and 23rd days. The course of treatment is from 5 to 10 receptions, depending on the severity of the condition and the severity of clinical symptoms.

In case of herpes infection, the drug is taken on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th day of treatment. The course of treatment may vary depending on the severity of the condition and the severity of the clinical symptoms.

For emergency non-specific prophylaxis of influenza and acute respiratory infections (with direct contact with patients with influenza or acute respiratory infections of a different etiology, during an influenza epidemic): on the 1st, 2nd, 4th, 6th, 8th day. Then they take a break of 72 hours (3 days) and continue the course for 11, 14, 17, 20, 23 days. The general course is from 5 to 10 receptions.

Enteric-coated yellow tablets, round, biconvex; cross-section - yellow core.

1 tab.

meglumine acridone acetate * (calculated as acridoneacetic acid) 150 mg

* obtained according to the following recipe: acridoneacetic acid - 150 mg, meglumine (N-methylglucamine) - 146 mg.

Excipients: povidone K30 - 7.93 mg, calcium stearate - 3.07 mg, hypromellose - 2.73 mg, polysorbate 80 - 0.27 mg.

• Liver cirrhosis in the stage of decompensation;

• children under 4 years of age (due to imperfect swallowing);

• pregnancy;

• breastfeeding period;

• individual intolerance to the components of the drug.

• The drug should be used with caution in diseases of the digestive system in the acute phase (erosion, stomach and / or duodenal ulcers, gastritis, duodenitis) and a history of allergic reactions. Before taking the drug, patients with these diseases should consult a doctor.

pharmachologic effect

Meglumine acridone acetate is a low-molecular-weight interferon inducer, which determines a wide range of its biological activity (antiviral, immunomodulatory, anti-inflammatory).

CycloferonЃ is effective against herpes viruses, influenza and other pathogens of acute respiratory diseases.

It has a direct antiviral effect, suppressing the reproduction of the virus in the early stages (1-5 days) of the infectious process, reducing the virulence of the viral progeny, leading to the formation of defective viral particles. Increases the body's nonspecific resistance against viral and bacterial infections.

Pharmacokinetics

Suction

After taking the drug orally in a daily dose, Cmax in blood plasma is reached after 2-3 hours, the concentration gradually decreases by 8 hours, after 24 hours the active substance is found in trace amounts.

Withdrawal

T1 / 2 is 4-5 hours. The use of CycloferonЃ in recommended doses does not create conditions for its accumulation in the body.

Side effect

From the immune system: very rarely - angioedema.

Skin and subcutaneous tissue disorders: very rarely - rash, urticaria.

If any of the undesirable effects indicated in the instructions are aggravated or any other undesirable effects not specified in the instructions are noted, the patient should be informed about this by the doctor.

Application during pregnancy and lactation

The use of the drug during pregnancy and during breastfeeding is contraindicated.

Application for violations of liver function

The use of the drug is contraindicated in liver cirrhosis in the stage of decompensation.

Application in children

The drug is contraindicated for use in children under 4 years of age (due to imperfect swallowing).

special instructions

For diseases of the thyroid gland, an endocrinologist must be consulted before using CycloferonЃ.

If the next dose of the drug is missed, then the course of treatment should be continued as soon as possible without taking into account the time interval and doubling the dose.

In the absence of a therapeutic effect, the patient should consult a doctor.

Influence on the ability to drive vehicles and mechanisms

CycloferonЃ does not affect the ability to drive vehicles.

Overdose

There are no data on drug overdose.

Drug interactions

CycloferonЃ is compatible with all drugs used in the treatment of these diseases (including interferons, chemotherapeutic, symptomatic drugs).

CycloferonЃ enhances the effect of interferons and nucleoside analogs.

When used together, CycloferonЃ reduces the side effects of chemotherapy and interferon therapy.