deslor atadine | Desloratadine Canon tablets coated. 5 mg 10 pcs.
Special Price
$16.66
Regular Price
$24.00
In stock
SKU
BID489724
Latin name
DESLORATADINE CANON
DESLORATADINE CANON
Latin name
DESLORATADINE CANON
Release form
Film-coated tablets of white or almost white color, round, biconvex in cross section of almost white or white with a creamy or white with a pinkish tint.
packaging 10 pcs
Pharmacological action
Pharmaceutical group: antiallergic drug - H1-histamine receptor blocker. Srdlp Pharmaceutical action:
Desloratadine Canon is a long-acting antihistamine
is the primary active metabolite of loratadine and inhibits a cascade of allergic inflammation reactions, including the release of inflammatory cytokines, including interleukins IL-4, IL-6, IL-8, IL-13, the release of pro-inflammatory chemokines (RANTES), production of superoxide anions by activated polymorphonuclear neutrophils, adhesion and chemotaxis of eosinophils, isolation of adhesion molecules such as P-selectin, IgE-mediated release of histamine, prostaglandin D2 and leukotriene C4.
Thus, it prevents the development and facilitates the course of allergic reactions, has an antipruritic and antiexudative effect, reduces capillary permeability, prevents the development of tissue edema, smooth muscle spasm.
The drug does not affect the central nervous system, practically does not have a sedative effect (does not cause drowsiness) and does not affect the speed of psychomotor reactions. Does not cause prolongation of the QT interval on the ECG.
Desloratadine begins within 30 minutes after ingestion and lasts 24 hours.
Pharmacokinetics: Only a small portion of the oral dose is excreted by the kidneys (<2%) and through the intestines (<7%). The elimination half-life is 20-30 hours (on average - 27 hours).
Indications
- Allergic rhinitis (elimination or relief of sneezing, nasal congestion, nasal mucus, itching in the nose, itching of the palate, itching and redness of the eyes, lacrimation)
- urticaria (reduction or elimination of skin itching, rash).
Contraindications
- Hypersensitivity to any of the substances that make up the
preparation - pregnancy and lactation
- under the age of 12 years.
Precautions: Severe chronic renal failure.
Use during pregnancy and lactation
The drug Desloratadine Canon is not recommended for use during pregnancy, as there have been no clinical trials and the safety of use during pregnancy has not been established.
Desloratadine passes into breast milk, therefore, women who are breast-feeding should not take Desloratadine Canon.
Composition of
1 tablet: - desloratadine 5 mg
excipients:
calcium hydrogen phosphate dihydrate 61.7 mg
povidone 6.8 mg
calcium stearate 0.7 mg croscarmellose sodium
(primrose 4) 8 mg
microcrystalline cellulose 41 mg
film composition:
Opadry II white 4 mg, including: 1.88 mg polyvinyl alcohol, macrogol (polyethylene glycol 3350) 0.94 mg, talc 0.7 mg, titanium dioxide 0, 48 mg
Dosage and administration
Inside, regardless of food intake, adults and adolescents from 12 years old 1 tablet per day. The tablet should be swallowed whole, washed down with water.
Side effects
WHO classification of the incidence of side effects: very often - 1/10 prescriptions (> 10%)
often - from 1/100 to <1/10 prescriptions (> 1% and infrequently from 1 / 1000 to 0.1% and rarely - from 1/10000 to 0.01% and very rare - Disorders from the
immune system Very rarely: allergic reactions, including anaphylaxis.
Disorders from the nervous system
Infrequently: headache.
Disorders from heart
Very rare: tachycardia, palpitations
Disorders of the gastrointestinal tract
Infrequently: dry mouth.
Disorders of the skin and subcutaneous tissue
Very rare: rash.
General disorders and disorders at the injection site
Often: fatigue.
Laboratory and instrumental data
Very rare: increased activity of liver enzymes, increased bilirubin concentration.
Drug Interaction
No interaction with other drugs. Eating does not affect the effectiveness of the drug. Desloratadine does not increase the effect of alcohol on the central nervous system.
Active ingredient
Desloratadine
Conditions of dispensation from pharmacies
By retseptu
lekarstvennaja form
tablets
Indications
Indications
Dermatitis, Allergic conjunctivitis, Diathesis, Allergic rhinitis, Allergy, Urticaria, Pollinosis
Kanonfarma, Russia
DESLORATADINE CANON
Release form
Film-coated tablets of white or almost white color, round, biconvex in cross section of almost white or white with a creamy or white with a pinkish tint.
packaging 10 pcs
Pharmacological action
Pharmaceutical group: antiallergic drug - H1-histamine receptor blocker. Srdlp Pharmaceutical action:
Desloratadine Canon is a long-acting antihistamine
is the primary active metabolite of loratadine and inhibits a cascade of allergic inflammation reactions, including the release of inflammatory cytokines, including interleukins IL-4, IL-6, IL-8, IL-13, the release of pro-inflammatory chemokines (RANTES), production of superoxide anions by activated polymorphonuclear neutrophils, adhesion and chemotaxis of eosinophils, isolation of adhesion molecules such as P-selectin, IgE-mediated release of histamine, prostaglandin D2 and leukotriene C4.
Thus, it prevents the development and facilitates the course of allergic reactions, has an antipruritic and antiexudative effect, reduces capillary permeability, prevents the development of tissue edema, smooth muscle spasm.
The drug does not affect the central nervous system, practically does not have a sedative effect (does not cause drowsiness) and does not affect the speed of psychomotor reactions. Does not cause prolongation of the QT interval on the ECG.
Desloratadine begins within 30 minutes after ingestion and lasts 24 hours.
Pharmacokinetics: Only a small portion of the oral dose is excreted by the kidneys (<2%) and through the intestines (<7%). The elimination half-life is 20-30 hours (on average - 27 hours).
Indications
- Allergic rhinitis (elimination or relief of sneezing, nasal congestion, nasal mucus, itching in the nose, itching of the palate, itching and redness of the eyes, lacrimation)
- urticaria (reduction or elimination of skin itching, rash).
Contraindications
- Hypersensitivity to any of the substances that make up the
preparation - pregnancy and lactation
- under the age of 12 years.
Precautions: Severe chronic renal failure.
Use during pregnancy and lactation
The drug Desloratadine Canon is not recommended for use during pregnancy, as there have been no clinical trials and the safety of use during pregnancy has not been established.
Desloratadine passes into breast milk, therefore, women who are breast-feeding should not take Desloratadine Canon.
Composition of
1 tablet: - desloratadine 5 mg
excipients:
calcium hydrogen phosphate dihydrate 61.7 mg
povidone 6.8 mg
calcium stearate 0.7 mg croscarmellose sodium
(primrose 4) 8 mg
microcrystalline cellulose 41 mg
film composition:
Opadry II white 4 mg, including: 1.88 mg polyvinyl alcohol, macrogol (polyethylene glycol 3350) 0.94 mg, talc 0.7 mg, titanium dioxide 0, 48 mg
Dosage and administration
Inside, regardless of food intake, adults and adolescents from 12 years old 1 tablet per day. The tablet should be swallowed whole, washed down with water.
Side effects
WHO classification of the incidence of side effects: very often - 1/10 prescriptions (> 10%)
often - from 1/100 to <1/10 prescriptions (> 1% and infrequently from 1 / 1000 to 0.1% and rarely - from 1/10000 to 0.01% and very rare - Disorders from the
immune system Very rarely: allergic reactions, including anaphylaxis.
Disorders from the nervous system
Infrequently: headache.
Disorders from heart
Very rare: tachycardia, palpitations
Disorders of the gastrointestinal tract
Infrequently: dry mouth.
Disorders of the skin and subcutaneous tissue
Very rare: rash.
General disorders and disorders at the injection site
Often: fatigue.
Laboratory and instrumental data
Very rare: increased activity of liver enzymes, increased bilirubin concentration.
Drug Interaction
No interaction with other drugs. Eating does not affect the effectiveness of the drug. Desloratadine does not increase the effect of alcohol on the central nervous system.
Active ingredient
Desloratadine
Conditions of dispensation from pharmacies
By retseptu
lekarstvennaja form
tablets
Indications
Indications
Dermatitis, Allergic conjunctivitis, Diathesis, Allergic rhinitis, Allergy, Urticaria, Pollinosis
Kanonfarma, Russia
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