Dexpanthenol | D-Panthenol-Nizhpharm cream for external use 5% 50 g

Pharmacological action

Dexpanthenol - a derivative of pantothenic acid. Dexpanthenol in the body passes into pantothenic acid, which is an integral part of coenzyme A and is involved in the processes of acetylation, in the synthesis of acetylcholine, corticosteroids, porphyrins. Moreover, It takes part in almost all metabolic processes (the tricarboxylic acid cycle, the metabolism of carbohydrates, fats and fatty acids, phospholipids, proteins, etc.), stimulates the regeneration of the skin, mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerative, metabolic and weak anti-inflammatory effect.

When applied topically, it is rapidly absorbed by the skin and turns into pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin). Its concentration in the blood is 0.5-1 mg / l, in the blood serum - 100 μg / l. Pantothenic acid is not metabolized in the body (except for inclusion in Co-A), it is excreted unchanged.

Indications

In case of violation of the integrity of the skin: healing of burns (including solar), minor skin lesions (abrasions, cuts, cracks, etc.).

Prevention and treatment of dry skin, including as a consequence of dermatitis of various origins (manifested by peeling, redness, irritation, tightness), as well as daily care for areas of the skin that are most affected by external factors (face, hands), including due to chapping.

For the care of the mammary gland during lactation (cracks and redness of the nipples of the breast), for the care of infants and babies (diaper rash, diaper dermatitis).

Contraindications

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation

The drug can be used during pregnancy and during breastfeeding. If the drug is used to treat nipple cracks during lactation, it should be washed off before breastfeeding.

Special instructions

For external use only. Do not apply to wet wounds.

Impact on the ability to drive vehicles and mechanisms. The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Composition of

1 g of cream contains: active ingredient: dexpanthenol 50 mg

excipients: propylene glycol 100 mg, methyl parahydroxybenzoate 0.8 mg, propyl parahydroxybenzoate 0.2 mg, macrogol cetostearate 16 mg, ethyl acetate %, stearyl alcohol at least 40%] 40 mg, liquid paraffin 80 mg, petrolatum 100 mg, sodium hydrogen phosphate dodecahydrate 0.2 mg, potassium dihydrogen phosphate 7.8 mg, purified water up to 1 g.

Dosage and Administration

Externally. The cream is applied a thin layer 1-2 times a day on previously cleaned, dry skin and rubbed lightly.

When caring for the mammary gland, the cream is applied to the surface of the nipples after each feeding.

When taking care of babies, the cream is applied with each change of diapers (diapers, diapers).

Side effects

Allergic reactions. Allergic skin reactions (e.g. contact dermatitis, allergic dermatitis, itching, redness, eczema, rash, urticaria, skin irritation). If any of the side effects indicated in the instructions are exacerbated, or any other side effects not listed in the instructions are noted, immediately inform your doctor.

Drug Interactions

Cases of interaction with other drugs are unknown.

Overdose

Cases of overdose unknown.

Storage conditions

At a temperature not exceeding 25 РC.

Keep out of the reach and sight of children.

Expiration

2 years.

active substance

Dexpanthenol

Pharmacy terms

Without a prescription

Dosage form

cream