Elkar oral solution 30%, 100ml

The drug is used as part of complex therapy.

Х intense physical activity and psychoemotional stress: to improve performance, endurance, reduce fatigue, including in the elderly;
Х during the period of rehabilitation after illnesses and surgical interventions, injuries, including for the acceleration of tissue regeneration;
Х complex therapy of chronic gastritis and chronic pancreatitis with reduced secretory function;
Х complex therapy of skin diseases (psoriasis, seborrheic eczema, focal scleroderma and discoid lupus erythematosus);
Х mild hyperthyroidism;
Х neurological manifestations in vascular, toxic and traumatic brain damage;
Х anorexia nervosa syndrome;
Х diseases accompanied by a lack of carnitine or its increased loss (myopathy, cardiomyopathy, mitochondrial diseases, hereditary diseases with concomitant mitochondrial insufficiency) - to compensate for its deficiency as part of complex therapy;
Х in pediatric practice (treatment of children under 3 years of age under the supervision of a doctor): when nursing premature babies, newborns who have suffered a birth trauma or asphyxiation; children with a sluggish sucking reflex and low weight gain; reduced muscle tone, with insufficient development of motor and mental functions, as well as with the aim of preventing these disorders in children of the 'risk group'; with growth retardation and underweight in children and adolescents under 16 years old.
Х in adults in sports medicine and during intensive training (during the training process when working out aerobic performance): to improve speed-strength indicators and coordination of movements, to increase muscle mass and reduce body fat mass, to prevent post-workout syndrome (accelerate recovery processes after physical activity), with traumatic injuries in order to accelerate muscle regeneration.

The drug is used as part of complex therapy.

Inside 30 minutes before meals, additionally diluted with liquid.

With prolonged physical and psycho-emotional stress: from 0.75 g (1/2 measuring spoon or 2.5 ml) 3 times a day to 2.25 g (1.5 measuring spoon or 7.5 ml) 2-3 times a day.

With anorexia nervosa, as well as during the period of rehabilitation after illnesses and surgical interventions and injuries: 1.5 g (1 measuring spoon or 5 ml) 2 times a day. The course of treatment is within 1-2 months. In the complex therapy of chronic gastritis and chronic pancreatitis with reduced secretory function: 0.375 g (1/4 measuring spoon or 1.25 ml) 2 times a day. The course of treatment is within 1-1.5 months.

For the treatment of skin diseases: 0.75 g each (1/2 measuring spoon or 2.5 ml). The course of treatment is within 2-4 weeks.

With mild hyperthyroidism: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after a 1-2 month break or is prescribed for 3 months without a break.

For vascular, toxic and traumatic brain lesions: 0.75 g (1/2 measuring spoon or 2.5 ml) per day. The course of treatment is within 3-5 days. If necessary, a second course is prescribed after 12-14 days.

For diseases accompanied by a lack of carnitine (primary and secondary carnitine deficiency): up to 50-100 mg / kg (2-5 drops / kg) body weight with a frequency of administration 2-3 times a day. The course of treatment is within 3-4 months.

Children are prescribed as an additive to sweet dishes (jelly, compote, juices). For children under 3 years of age, the dose is determined by the attending physician. From 3 to 6 years old - in a single dose of 0.1 g (5 drops) 2-3 times a day, in a daily dose of 0.2-0.3 g (11-16 drops). The course of treatment is 1 month. Children from 6 to 12 years old are prescribed in a single dose of 0.2-0.3 g (11-16 drops) 2-3 times a day, in a daily dose of 0.4-0.9 g (22-48 drops). The course of treatment is at least 1 month.

With growth retardation: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after a 1-2 month break or is prescribed for 3 months without a break.

In sports medicine and with intensive training: 2.5 g 1-3 times a day (daily dose 2.5 -7.5 g); in the case of medical use -70-100 mg / kg / day (5-7.5 g / day). Reception courses: 3-4 weeks in the pre-competition period. During the training process - up to 6-8 weeks.

active substance: levocarnitine (Karnifit) - 300 mg;

auxiliary substances: citric acid monohydrate - 1.2 mg, methyl parahydroxybenzoate - 0.5 mg, propyl parahydroxybenzoate - 0.2 mg, purified water up to 1 ml.

Individual intolerance.

Trade name of the drug:

ElkarЃ.

International non-proprietary name:

levocarnitine.

Dosage form:

oral solution.

Description:

transparent colorless or slightly colored liquid. The presence of a specific smell is allowed.

Composition:

active substance: levocarnitine (Karnifit) - 300 mg;

auxiliary substances: citric acid monohydrate - 1.2 mg, methyl parahydroxybenzoate - 0.5 mg, propyl parahydroxybenzoate - 0.2 mg, purified water up to 1 ml.

Pharmacotherapeutic group:

metabolic agent.

ATX code:

A16AA01.

Pharmacological properties

Pharmacodynamics. L-carnitine is a natural substance related to vitamins of group B. It participates in metabolic processes as a carrier of long-chain fatty acids (palmitic, etc.) from the cytoplasm into mitochondria, where these acids undergo a process (3-oxidation with the formation of adenosine triphosphoric acid and acetyl- CoA. Improves protein and fat metabolism, increases the secretion and enzymatic activity of gastric and intestinal juices, improves food absorption, reduces excess body weight and reduces muscle fat. Increases resistance to physical activity, inhibits the formation of keto acids and anaerobic glycolysis, reduces the degree of lactic acidosis, promotes economical use of glycogen and increases its reserves in the liver and muscles.

It has anabolic and lipolytic effects. Normalizes increased basal metabolism in hyperthyroidism: it is a peripheral (indirect) antagonist of the action of thyroid hormones, and not a direct inhibitor of thyroid function. Improves metabolism and energy supply to tissues.

Pharmacokinetics. It is well absorbed in the intestines, the concentration in the blood plasma reaches a maximum after 3 hours and remains in the therapeutic range for 9 hours. Easily penetrates the liver, myocardium, more slowly - into the muscles. It is excreted by the kidneys, mainly in the form of acyl esters.

Indications for use

The drug is used as part of complex therapy.

Х intense physical activity and psychoemotional stress: to improve performance, endurance, reduce fatigue, including in the elderly;
Х during the period of rehabilitation after illnesses and surgical interventions, injuries, including for the acceleration of tissue regeneration;
Х complex therapy of chronic gastritis and chronic pancreatitis with reduced secretory function;
Х complex therapy of skin diseases (psoriasis, seborrheic eczema, focal scleroderma and discoid lupus erythematosus);
Х mild hyperthyroidism;
Х neurological manifestations in vascular, toxic and traumatic brain damage;
Х anorexia nervosa syndrome;
Х diseases accompanied by a lack of carnitine or its increased loss (myopathy, cardiomyopathy, mitochondrial diseases, hereditary diseases with concomitant mitochondrial insufficiency) - to compensate for its deficiency as part of complex therapy;
Х in pediatric practice (treatment of children under 3 years of age under the supervision of a doctor): when nursing premature babies, newborns who have suffered a birth trauma or asphyxiation; children with a sluggish sucking reflex and low weight gain; reduced muscle tone, with insufficient development of motor and mental functions, as well as with the aim of preventing these disorders in children of the 'risk group'; with growth retardation and underweight in children and adolescents under 16 years old.
Х in adults in sports medicine and during intensive training (during the training process when working out aerobic performance): to improve speed-strength indicators and coordination of movements, to increase muscle mass and reduce body fat mass, to prevent post-workout syndrome (accelerate recovery processes after physical activity), with traumatic injuries in order to accelerate muscle regeneration.

Contraindications

Individual intolerance.

Method of administration and dosage