Erythromycin ointment 10000ED, 15g

Infections of the skin and soft tissues: pustular skin diseases (including juvenile acne), infected wounds, bedsores, II-III degree burns, trophic ulcers.

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Apply to the affected skin 2-3 times / day.

The duration of treatment is 1.5-2 months.

1g

Active ingredient: erythromycin - 10 thousand units

Excipients: anhydrous lanolin, sodium disulfite (sodium metabisulfite, sodium pyrosulfite), petroleum jelly.

Hypersensitivity to erythromycin and other macrolides.

Description:

Ointment for external use from light yellow to brownish yellow.

Ingredients: 1g

Active ingredient: erythromycin - 10 thousand units

Excipients: anhydrous lanolin, sodium disulfite (sodium metabisulfite, sodium pyrosulfite), petroleum jelly.

Clinical and pharmacological group: Antibiotic for external use

Pharmaco-therapeutic group: Antibiotic, macrolide

pharmachologic effect

Antibiotic of the macrolide group. Has a bacteriostatic effect. However, in high doses, it has a bactericidal effect against sensitive microorganisms. Erythromycin reversibly binds to bacterial ribosomes, thereby inhibiting protein synthesis.

Active against gram-positive bacteria: Staphylococcus spp. (strains producing and not producing penicillinase), Streptococcus spp. (including Streptococcus pneumoniae); gram-negative bacteria: Neisseria gonorrhoeae, Haemophilus influenzae, Bordetella pertussis, Brucella spp., Legionella spp., Bacillus anthracis, Corynebacterium diphtheriae; anaerobic bacteria: Clostridium spp.

Erythromycin is also active against Mycoplasma spp., Chlamydia spp., Spirochaetaceae, Rickettsia spp.

Gram-negative bacilli are resistant to erythromycin, incl. Escherichia coli, Pseudomonas aeruginosa, Shigella spp., Salmonella spp.

Pharmacokinetics

plasma is 70-90%. It is metabolized in the liver, partly with the formation of inactive metabolites. T1 / 2 - 1.4-2 hours. It is excreted in bile and urine.

Indications of the active substances of the drug Erythromycin

Infections of the skin and soft tissues: pustular skin diseases (including juvenile acne), infected wounds, bedsores, II-III degree burns, trophic ulcers.

Dosage regimen

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Apply to the affected skin 2-3 times / day.

The duration of treatment is 1.5-2 months.

Side effect

Local reactions: flushing, burning, itching, irritation and peeling of the skin.

Contraindications for use

Hypersensitivity to erythromycin and other macrolides.

Application during pregnancy and lactation

Erythromycin crosses the placental barrier and is excreted in breast milk.

When using erythromycin externally during pregnancy and lactation, the intended benefit to the mother and the potential risk to the fetus or infant should be assessed.

Application for violations of liver function

Use with caution in case of liver dysfunction.

Application for impaired renal function

Use with caution in case of impaired renal function.

Application in children

Application is possible according to the dosage regimen.

Use in elderly patients

Use with caution in elderly patients.

special instructions

With prolonged use, superinfection may develop.

Before using any other anti-acne medicinal product for external use, at least 1 hour should pass.

Drug interactions

Shows antagonism with lincomycin, clindamycin and chloramphenicol.

Reduces the bactericidal effect of beta-lactam antibiotics (penicillins, cephalosporins, carbapenems).

With the simultaneous use of dosage forms of erythromycin for external use with abrasive substances that lead to excessive irritation of the skin, as well as with drugs that cause peeling of the skin, a cumulative irritant or drying effect is possible.

Storage conditions

Store in its original packaging at a temperature not exceeding 15 ? C out of the reach of children.

Shelf life is 3 years.