indometacin indometacin | methindole tablets retard 75 mg, 50 pcs.
Special Price
$18.62
Regular Price
$26.00
In stock
SKU
BID494447
Latin name
Metin dol retard
Metin dol retard
Latin name
Metin dol retard
Packing
In a blister pack of 25 tablets. In the package 2 blisters.
Indications
rheumatic diseases,
collagenosis,
sciatica,
peripheral neuritis,
discopathy,
gout (exacerbation),
acute radicular pain syndromes.
Contraindications
hypersensitivity,
gastric ulcer and duodenal ulcer,
enteritis,
enterocolitis,
bronchial asthma,
childhood (up to 14 years).
Use during pregnancy and lactation
Contraindicated.
Composition
In 1 tablet of prolonged action contains:
Active ingredient: indomethacin 75 mg.
Excipients: microcrystalline cellulose,
potato starch,
methacrylic acid copolymer,
talc,
magnesium stearate.
Dosage and administration
Metindol retard is taken orally, without chewing, during or immediately after a meal, with plenty of water or milk.
Adults: 1 or 2 tablets per day, depending on the severity of the disease and individual sensitivity.
Do not exceed a dose of more than 150 mg per day.
Side effects of
dyspeptic disorders,
gastrointestinal bleeding,
anorexia,
relapse of gastric ulcer and duodenal ulcer,
headaches,
dizziness,
confusion,
convulsions,
hypertension,
edema.
Drug Interaction
Increases plasma concentrations of digoxin, methotrexate and lithium preparations, which may increase their toxicity.
Ethanol, colchicine, ACS and corticotropin increase the risk of gastrointestinal bleeding.
Enhances the hypoglycemic action of insulin and oral hypoglycemic drugs enhances the effect of indirect anticoagulants, antiplatelet agents, thrombolytics (alteplase, streptokinase and urokinase) - there is a risk of bleeding.
Reduces the effect of diuretics, against the background of the use of potassium-sparing diuretics increases the risk of hyperkalemia, reduces the effectiveness of uricosuric and antihypertensive drugs (including beta-blockers), enhances the side effects of glucocorticosteroids,.
Cyclosporine and gold preparations increase nephrotoxicity (apparently due to the suppression of prostaglandin synthesis in the kidneys).
Cefamandol, cefaperazone, cefotetan, valproic acid, plicamycin increase the incidence of hypoprotrombinemia and the risk of bleeding.
Antacids and cholestyramine reduce indomethacin absorption.
Increases the toxicity of zidovudine (by inhibiting metabolism) in newborns increases the risk of developing toxic effects of aminoglycosides (because it decreases renal clearance and increases blood concentration).
Concurrent administration with serotonin reuptake inhibitors increases the risk of gastrointestinal bleeding.
Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.
Co-administration with paracetamol increases the risk of nephrotoxic effects.
Overdose
Symptoms: nausea, vomiting, severe headache, dizziness, memory impairment and disorientation. In more severe cases, paresthesias, numbness of the limbs and convulsions are observed.
Treatment: is the rapid removal of the drug from the body and the use of appropriate symptomatic agents. Indomethacin cannot be excreted by hemodialysis.
Storage conditions
Store in a dry, dark place at a temperature of 15-25 РC.
Keep out of the reach of children.
Do not use after expiration date.
Expiration
5 years.
Deystvuyuschee substances
indometacin
Dosage form
Dosage form
tablets prolong.
Ai Ann Polfa Rzeszow AO, Poland
Metin dol retard
Packing
In a blister pack of 25 tablets. In the package 2 blisters.
Indications
rheumatic diseases,
collagenosis,
sciatica,
peripheral neuritis,
discopathy,
gout (exacerbation),
acute radicular pain syndromes.
Contraindications
hypersensitivity,
gastric ulcer and duodenal ulcer,
enteritis,
enterocolitis,
bronchial asthma,
childhood (up to 14 years).
Use during pregnancy and lactation
Contraindicated.
Composition
In 1 tablet of prolonged action contains:
Active ingredient: indomethacin 75 mg.
Excipients: microcrystalline cellulose,
potato starch,
methacrylic acid copolymer,
talc,
magnesium stearate.
Dosage and administration
Metindol retard is taken orally, without chewing, during or immediately after a meal, with plenty of water or milk.
Adults: 1 or 2 tablets per day, depending on the severity of the disease and individual sensitivity.
Do not exceed a dose of more than 150 mg per day.
Side effects of
dyspeptic disorders,
gastrointestinal bleeding,
anorexia,
relapse of gastric ulcer and duodenal ulcer,
headaches,
dizziness,
confusion,
convulsions,
hypertension,
edema.
Drug Interaction
Increases plasma concentrations of digoxin, methotrexate and lithium preparations, which may increase their toxicity.
Ethanol, colchicine, ACS and corticotropin increase the risk of gastrointestinal bleeding.
Enhances the hypoglycemic action of insulin and oral hypoglycemic drugs enhances the effect of indirect anticoagulants, antiplatelet agents, thrombolytics (alteplase, streptokinase and urokinase) - there is a risk of bleeding.
Reduces the effect of diuretics, against the background of the use of potassium-sparing diuretics increases the risk of hyperkalemia, reduces the effectiveness of uricosuric and antihypertensive drugs (including beta-blockers), enhances the side effects of glucocorticosteroids,.
Cyclosporine and gold preparations increase nephrotoxicity (apparently due to the suppression of prostaglandin synthesis in the kidneys).
Cefamandol, cefaperazone, cefotetan, valproic acid, plicamycin increase the incidence of hypoprotrombinemia and the risk of bleeding.
Antacids and cholestyramine reduce indomethacin absorption.
Increases the toxicity of zidovudine (by inhibiting metabolism) in newborns increases the risk of developing toxic effects of aminoglycosides (because it decreases renal clearance and increases blood concentration).
Concurrent administration with serotonin reuptake inhibitors increases the risk of gastrointestinal bleeding.
Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.
Co-administration with paracetamol increases the risk of nephrotoxic effects.
Overdose
Symptoms: nausea, vomiting, severe headache, dizziness, memory impairment and disorientation. In more severe cases, paresthesias, numbness of the limbs and convulsions are observed.
Treatment: is the rapid removal of the drug from the body and the use of appropriate symptomatic agents. Indomethacin cannot be excreted by hemodialysis.
Storage conditions
Store in a dry, dark place at a temperature of 15-25 РC.
Keep out of the reach of children.
Do not use after expiration date.
Expiration
5 years.
Deystvuyuschee substances
indometacin
Dosage form
Dosage form
tablets prolong.
Ai Ann Polfa Rzeszow AO, Poland
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