Streptophagus bottle solution 20 ml 4 pcs.

Special Price $35.28 Regular Price $43.00
In stock
SKU
BIDL3178235347C

Russian Pharmacy name:

Стрептофаг 4 шт. флакон раствор для приема внутрь местного и наружного применения 20 мл

Packaging and release form

Solution for oral, local and external use 20 - 4 bottles with instructions for use per pack.

Dosage form

It is a transparent yellow liquid of varying intensity, with a possible greenish tint.

Compound

1 ml of the drug contains:
Active ingredients.
Purified bacteriophages of the genus Streptococcus (with Appelman activity of at least 10-5) - up to 1 ml.
Excipient.
8-hydroxyquinoline sulfate monohydrate (preservative) in terms of 8-hydroxyquinoline sulfate - 0.0001 g/ml (calculated content).
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Pharmacotherapeutic group

~

Pharmacodynamics

The drug has the ability to specifically lyse bacteria of the genus Streptococcus.

Indications

treatment and prevention of diseases caused by Streptococcus bacteria as part of complex therapy:
- diseases of the ear, throat, nose, respiratory tract and lungs (inflammation of the sinuses, middle ear, sore throat, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy);
- surgical infections (wound suppuration, burns, abscess, phlegmon, boils, carbuncles, hidradenitis, panaritium, paraproctitis, mastitis, bursitis, osteomyelitis);
- urogenital infections (urethritis, cystitis, pyelonephritis, colpitis, endometritis, salpingoophoritis);
- enteral infections (gastroenterocolitis, cholecystitis), intestinal dysbiosis;
- generalized septic diseases;
- purulent-inflammatory diseases of newborns (omphalitis, pyoderma, conjunctivitis, gastroenterocolitis, sepsis, etc.);
- other diseases caused by streptococci.
For prophylactic purposes, the drug is used for the treatment of post-operative and newly infected wounds, as well as for the prevention of nosocomial infections for epidemic indications.
An important condition for effective phage therapy is the preliminary determination of the phage sensitivity of the pathogen.
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Contraindications

Hypersensitivity to the components of the drug.

Directions for use and doses

The drug is used for oral administration (oral), rectal administration, applications, irrigation, administration into wound cavities, vagina, uterus, nose, sinuses and drained cavities.
RECOMMENDED DOSAGES OF THE DRUG
AGE OF THE PATIENT DOSE PER 1 ADMINISTRATION (ml)
inside as an enema
0-6 months 5 5-10
6-12 months 10 10-20
from 1 year to 3 years 15 20-30
from 3 to 8 years 15-20 30-40
from 8 years and older 20-30 40-50
Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug orally for 7-20 days (according to clinical indications).
If chemical antiseptics were used to treat wounds before using the bacteriophage, the wound should be thoroughly washed with a sterile 0.9% sodium chloride solution.
Depending on the source of infection, the bacteriophage is used:
1. In the form of irrigation, lotions and tamponing in a volume of up to 200 ml, depending on the size of the affected area. In case of an abscess, after removing the purulent contents using a puncture, the drug is administered in an amount less than the volume of the removed pus. In case of osteomyelitis, after appropriate surgical treatment, 10-20 ml of bacteriophage is poured into the wound.
2. When introduced into cavities (pleural, articular and other limited cavities) up to 100 ml, capillary drainage is left, through which the bacteriophage is injected over several days.
3. For cystitis, pyelonephritis, urethritis, the drug is taken orally. If the cavity of the bladder or renal pelvis is drained, the bacteriophage is administered through a cystostomy or nephrostomy 1-2 times a day
20-50 ml into the bladder and 5-7 ml into the renal pelvis.
4. For purulent-inflammatory gynecological diseases, the drug is administered into the cavity of the vagina, uterus in a dose of 5-10 ml once daily, for colpitis - 10 ml by irrigation or tamponing 2 times a day. Tampons are placed for 2 hours.
5. For purulent-inflammatory diseases of the ear, throat, nose, the drug is administered in a dose of 2-10 ml 1-3 times a day. The bacteriophage is used for rinsing, washing, instilling, introducing moistened turundas (leaving them for 1 hour).
6. For enteral infections and intestinal dysbiosis, the drug is taken orally 3 times a day 1 hour before meals for 7 to 20 days according to clinical indications. It is possible to combine double oral administration with a single rectal administration of a single age-specific dose of the bacteriophage in the form of an enema after bowel movement.
Use of bacteriophage in children (up to 6 months). For sepsis and enterocolitis in newborns, including premature babies, the bacteriophage is used in the form of high enemas (through a gas tube or catheter) 2-3 times a day in a dose of 5-10 ml. In the absence of vomiting and regurgitation, it is possible to use the drug by mouth. In this case, it is mixed with breast milk. A combination of rectal (in the form of high enemas) and oral (through the mouth) use of the drug is possible. The course of treatment is 5-15 days. In case of recurrent course of the disease, repeated courses of treatment are possible. In order to prevent sepsis and enterocolitis during intrauterine infection or the risk of nosocomial infection in newborns, the bacteriophage is used in the form of enemas 2 times a day for 5-7 days.
In the treatment of omphalitis, pyoderma, and infected wounds, the drug is used in the form of applications twice daily (a gauze pad is moistened with a bacteriophage and applied to the umbilical wound or affected area of ​​skin).
Precautions for use.
Before use, the vial with the bacteriophage must be shaken and inspected. The preparation must be transparent and free of sediment.
If cloudy, do not use the drug!
Due to the content of a nutrient medium in the drug, in which bacteria from the environment can develop, causing cloudiness of the drug, the following rules must be observed when opening the bottle:
- wash your hands thoroughly;
- treat the cap with an alcohol-containing solution;
- remove the cap without opening the stopper;
- do not place the cork with the inner surface on a table or other objects;
- do not leave the bottle open;
- Store an opened bottle only in the refrigerator.
Opening the bottle and removing the required volume of the drug can be done with a sterile syringe by piercing the stopper.
The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the shelf life.
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Side effects

Not installed.

Overdose

Symptoms of overdose, measures to assist in case of overdose. Not installed.

Drug interactions

The use of bacteriophage does not exclude the use of other antibacterial drugs.

special instructions

Use during pregnancy and breastfeeding.
The use of this drug during pregnancy and breastfeeding is possible in the presence of infections caused by phage-sensitive strains of streptococci (as recommended by a doctor).
Information about the possible effect of the drug on the ability to drive vehicles and machinery.
None.
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