Lactofiltrum tablets, No. 60

• intestinal microflora disorders, incl. as a result of antibiotic therapy;

• irritable bowel syndrome (as part of complex therapy);

• hepatitis and cirrhosis of the liver (as part of complex therapy);

• allergic diseases (atopic dermatitis, urticaria) - as part of complex therapy.

Inside, an hour before meals and other drugs, pre-chopped (if necessary), washed down with water.

Children from 1 to 3 years old - 1/2 tab. 3 times a day; 3-7 years - 1 table. 3 times a day; 8-12 years old - 1-2 tables. 3 times a day; adults and children over 12 years old - 2-3 tables. 3 times a day.

The average duration of the course of treatment is 2-3 weeks.

Long-term use of the drug and repeated courses of treatment should be carried out only on the recommendation of a doctor.

active substances: hydrolytic lignin (polyfan, in terms of dry matter) - 355 mg

lactulose (in terms of 100% substance) - 120 mg

excipients: sodium croscarmellose - 20 mg; magnesium stearate - 5 mg

• intestinal obstruction;

• gastrointestinal bleeding;

• galactosemia;

• hypersensitivity to the drug.

• With caution, the drug should be prescribed for exacerbation of gastric ulcer and duodenal ulcer, intestinal atony.

pharmachologic effect

Enterosorbent. The pharmacological action of the drug LaktofiltrumЃ is due to the properties of its active components - lignin and lactulose. Hydrolysis lignin is an enterosorbent of natural origin, consisting of products of hydrolysis of wood components, has a high sorbing activity and a nonspecific detoxification effect. Binds in the intestine and removes from the body pathogenic bacteria and bacterial toxins, drugs, heavy metal salts, ethanol, allergens, as well as excess of certain metabolic products, incl. bilirubin, cholesterol, histamine, serotonin, urea, and other metabolites responsible for the development of endogenous toxicosis. Lactulose is a synthetic disaccharide, the molecule of which consists of galactose and fructose residues.In the large intestine, lactulose as a substrate is fermented by the normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli. As a result of hydrolysis of lactulose in the large intestine, organic acids are formed - lactic, acetic and formic, which suppress the growth of pathogenic microorganisms and, as a result, reduce the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex action of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.suppressing the growth of pathogenic microorganisms and thereby reducing the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex action of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.suppressing the growth of pathogenic microorganisms and thereby reducing the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex action of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.

Pharmacokinetics

Hydrolytic lignin is not absorbed, completely excreted from the intestine within 24 hours. Lactulose in the stomach and upper intestine is not absorbed or hydrolyzed. Lactulose hydrolysis occurs in the colon.

Side effect

From the digestive system: rarely - flatulence, diarrhea. Others: allergic reactions.

Application during pregnancy and lactation

There are no data on the safety of using LactofiltrumЃ during pregnancy and lactation.

special instructions

The drug can be used in combination therapy with other drugs, subject to the rules of separate administration.

Overdose

Symptoms: constipation, abdominal pain. Treatment: discontinuation of the drug.

Drug interactions

A decrease in the therapeutic effect of some drugs taken simultaneously by mouth is possible.