Mahaldrat, simethicone | Antareit chewable tablets 800 / 40mg 24 pcs.

Pharmacological action

Combined drug whose action is due to the properties that make up its components. It has antacid, adsorbing, enveloping, carminative action.

Magaldrate

Magaldrate (aluminum magnesium hydroxide sulfate) neutralizes free hydrochloric acid in the stomach without causing secondary hypersecretion of gastric juice. Due to the increase in pH when it is taken, the peptic activity of gastric juice decreases. It has an absorbent and enveloping effect, due to which the effect of damaging factors on the mucous membrane of the stomach is reduced, it binds bile acids.

simethicone

simethicone changes the surface tension of gas bubbles, formed in the contents of the stomach and intestinal mucus, and causes their destruction. The gases released in this case can be absorbed by the cells of the intestinal wall, or excreted due to peristalsis. Simethicone removes foam in a purely physical way, does not enter into chemical reactions, is pharmacologically inert.

Pharmacokinetics:

Magaldrat

Absorption of aluminum and magnesium ions in the blood is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the content of aluminum and magnesium in the blood may increase to toxic values ​​as a result of a violation of their excretion.

Simethicone

Simethicone due to pharmacological and chemical inertness after oral administration is not absorbed into organs and tissues. After passing through the gastrointestinal tract (GIT), it is excreted unchanged by the intestine.

Indications

Symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, belching with an acidic taste, pain in the stomach (they appear irregularly), a feeling of fullness or heaviness in the epigastric region, flatulence, dyspepsia (including those caused by errors in diet, taking medications, alcohol abuse, coffee, nicotine).

Contraindications

Hypersensitivity to the drug components severe renal failure hypophosphatemia fructose intolerance (due to the presence of sorbitol in the preparation) children under 12 years of age.

Composition

1 chewable tablet 800/40 mg contains:

Active ingredients:

magaldrate - 800 mg,

simethicone (in terms of dimethylpolysiloxane) - 61.54 (40) mg.

Excipients:

ethyl cellulose - 36.00 mg,

macrogol - 4000 - 140.0 mg,

sorbitol - 513.18 mg,

sucralose - 4.32 mg,

aspartame - 5.0 mg,

caramel flavor - 12.96 mg

silicon colloidal dioxide - 9.0 mg,

glyceryl dibehenate - 18.0 mg.

Dosage and Administration

Inside. The tablets should be chewed carefully or kept in the mouth until

is completely absorbed.

Adults and teenagers 12 years of age or older: Unless otherwise recommended by your doctor, take 1-2

tablets shortly after meals. If necessary, you can repeat taking

drug after 2 hours.

The maximum daily dose for 800/40 mg tablets is 8 tablets.

Side effects

Allergic reactions, nausea, vomiting, taste disturbance, constipation, diarrhea.

With prolonged use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis, impaired renal function.

In patients with concomitant renal failure, thirst, decreased blood pressure, hyporeflexia.

Storage conditions

Store in a dry, dark place at a temperature not exceeding 25 РC.

Prescription terms and conditions from

pharmacies Over-the-counter

Dosage form of

resorption tablets

Appointment

lactating mothers prescribed by a doctor for adults Children over 12 years of age, Pregnant women prescribed by the doctor

Indications

reflux esophagitis, heartburn, flatulence

Selebriti Biopharma Ltd, India