mebendazole | Vermox tablets 100 mg, 6 pcs.

release form

tablets

Packing

6 pcs

Pharmacological action

Vermoxum is a broad-spectrum anthelmintic drug most effective in enterobiasis and trichocephalosis.

Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cell tubulin, and inhibits the synthesis of adenosine triphosphate (ATP).

Pharmacokinetics

Virtually not absorbed in the intestines. T1 / 22.5-5.5 hours. Communication with plasma proteins - 90%.

Unevenly distributed over organs, accumulates in adipose tissue, liver, helminth larvae. In the liver, it is metabolized to a 2-amino derivative. More than 90% of the dose is excreted with feces unchanged. The absorbed part (5-10%) is excreted by the kidneys.

Indications

enterobiosis

ascariasis

hookworm

strongyloidosis

trichocephaliasis

trichinosis

teniosis

echinococcosis crdcrismosrd



Contraindications

ulcerative colitis

Crohn's disease

liver failure

childhood (up to 2 years)

pregnancy and lactation

hypersensitivity to any component of the drug.

Use during pregnancy and lactation

The drug is contraindicated during pregnancy and during breastfeeding.

Composition of

1 tablet contains:

Active ingredient:

mebendazole 100 mg srldkl 5 mg

magnesium stearate - 3 mg

sodium saccharin - 5 mg

talc - 9 mg

corn starch - 71 mg

lactose monohydrate - 110 mg.

Dosage and administration

Inside, with a small amount of water.

Adults and children over 3 years of age: with enterobiosis - 100 mg once a day and mixed helminthiases - 100 mg in the morning and evening for 3 days. If the symptoms of the disease persist, it is recommended to repeat the treatment after 3 weeks.

Adults and children over 14 years of age: with echinococcosis in the first 3 days - 500 mg 2 times a day, in the next 3 days the dose is increased to 500 mg 3 times a day, then the dose is increased to 1000-1500 mg 3 times a day. The average duration of treatment for echinococcosis caused by Echinococcus granulosus is 4-6 weeks caused by Echinococcus multilocularis - up to two years. When trichenellosis on the 1st day - 200-300 mg 3 times a day, on the 2nd day - 200-300 mg 4 times a day, and from the 3rd to the 14th day - 500 mg 3 times in a day.

It is recommended that all family members be treated concurrently. With ascariasis, trichocephalosis, hookworm, teniosis, strongyloidosis and mixed helminthiases, in the morning and evening, 100 mg for 3 days.

Side effects

Dizziness, nausea, abdominal pain.

When used in high doses for a long time: vomiting, diarrhea, headache, allergic reactions (skin rash, urticaria, angioedema), increased activity of hepatic transaminases, hypercreatininemia, leukopenia, anemia, eosinophilia, hair loss, hematuria, cylinder.

Drug Interactions

Reduces the need for insulin in patients with diabetes.

Co-administration with lipophilic substances should be avoided.

Cimetidine can increase the concentration in the blood, carbamazepine and other metabolic inducers - lower the concentration of Vermox in the blood.

Overdose

Symptoms: abdominal pain, nausea, vomiting, diarrhea. When used in high doses for a long time: reversible impaired liver function, hepatitis, neutropenia.

Treatment: it is necessary to remove the drug from the stomach by causing vomiting or by washing the stomach, receiving activated charcoal.

Storage Conditions

At 15–30 РC.

Terms and conditions

prescription

dosage form

tablets

Possible product names

VERMOKS 0.1 N6 TABLE

Vermox 0.1g Tab. X6 (R)

Vermox 100mg No. 6 tab

VERMOKS 100MG. No. 6 TAB. / GEDEON RICHTER /

Vermox tablet 100mg N6

Gedeon Richter Vengriya