Metrogyl Denta dental gel, 20 g

• Infectious and inflammatory diseases of the periodontal and oral mucosa:

• acute and chronic gingivitis;

• acute necrotizing ulcerative gingivitis of Vincent;

• acute and chronic periodontitis;

• juvenile periodontitis;

• periodontal disease complicated by gingivitis;

• aphthous stomatitis;

• cheilitis;

• inflammation of the oral mucosa when wearing prostheses;

• postextraction alveolitis (inflammation of the socket after tooth extraction);

• periodontitis, periodontal abscess (as part of combination therapy).

Topically, for dental use only.

In case of gum disease (gingivitis) for adults and children over 6 years old, Metrogyl DentaЃ is applied to the gum area with a thin layer, with a finger or with a cotton swab, 2 times a day. After applying the gel, you should refrain from drinking and eating for 30 minutes. It is not recommended to wash off the gel. The duration of the course of treatment is on average 7-10 days.

In case of periodontitis after the removal of dental deposits, periodontal pockets are treated with Metrogyl DentaЃ gel and the gel is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel independently: Metrogyl DentaЃ is applied to the gum area 2 times a day for 7-10 days.

In case of aphthous stomatitis, Metrogyl DentaЃ is applied to the affected area of ??the oral mucosa 2 times a day for 7-10 days.

To prevent exacerbations of chronic gingivitis and periodontitis, Metrogyl DentaЃ gel is applied to the gum area 2 times a day for 7-10 days. Preventive courses of treatment are carried out 2-3 times a year.

To prevent post-extraction alveolitis after tooth extraction, the socket is treated with Metrogyl DentaЃ gel, then the gel is applied 2-3 times a day for 7-10 days.

Dental gel

1 g

active substances: metronidazole benzoate - 16 mg (equivalent to metronidazole - 10 mg) chlorhexidine digluconate 20% solution - 2.5 mg (equivalent to chlorhexidine digluconate - 0.5 mg)

excipients: propylene glycol, carbomer 940, disodium edetate, sodium saccharinate, levomenthol, sodium hydroxide, water

in plastic tubes of 5, 10, 20 g; 1 tube in a box.

• Individual intolerance to metronidazole, chlorhexidine, as well as nitroimidazole derivatives, intolerance to any components that make up the drug;

• children under 6 years of age.

Pharmacotherapeutic group

Antimicrobial agent

Pharmacological properties

The effectiveness of the drug is due to the presence of two antibacterial components in its composition:

a) metronidazole has an antibacterial effect against anaerobic bacteria that cause periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.

b) chlorhexidine - antiseptic and antimicrobial agent, effective against gram-positive and gram-negative aerobic and anaerobic bacteria ( Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp., Bacteroides fragilis ). Some strains of Pseudomonas spp., Proteus spp. Are weakly sensitive to the drug , as well as acid-resistant forms of bacteria, bacterial spores. Does not interfere with the functional activity of lactobacilli.

When applied topically, Metrogyl Denta gel is practically not absorbed.

Indications for use

Infectious and inflammatory diseases of the periodontal and oral mucosa:

- acute and chronic gingivitis;

- Acute ulcerative necrotizing Vincent's gingivitis;

- acute and chronic periodontitis;

- youthful periodontitis;

- periodontal disease complicated by gingivitis;

- aphthous stomatitis;

- cheilitis;

- inflammation of the oral mucosa when wearing prostheses;

- postextraction alveolitis (inflammation of the hole after tooth extraction);

- periodontitis, periodontal abscess (as part of combination therapy)

Contraindications

- hypersensitivity to metronidazole, chlorhexidine, nitroimidazole derivatives or other components of the drug;

- diseases of the blood system, including a history;

- diseases of the peripheral and central nervous system;

- children under 18 years of age.

Application during pregnancy and during breastfeeding

Due to the lack of clinical data, the safety of the drug during pregnancy and during breastfeeding has not been established. The use of the drug during pregnancy is not recommended. During the period of breastfeeding, if it is necessary to prescribe the drug, it is necessary to decide on the termination of breastfeeding.

Method of administration and dosage

Topically, for dental use only.

In case of gum disease (gingivitis): Metrogyl DentaЃ is applied to the gum area with a thin layer with a finger or with a cotton swab 2 times a day. After applying the gel, you should refrain from drinking and eating for 30 minutes. It is not recommended to wash off the gel. The duration of the course of treatment is on average 7-10 days.

In case of periodontitis: after removing dental deposits, periodontal pockets are treated with Metrogyl DentaЃ gel, and the gel is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel independently. Metrogyl DentaЃ is applied to the gum area 2 times a day for 7-10 days.

For aphthous stomatitis: Metrogyl DentaЃ is applied to the affected area of ??the oral mucosa 2 times a day for 7-10 days.

For the prevention of exacerbations of chronic gingivitis and periodontitis: Metrogyl DentaЃ gel is applied to the gum area 2 times a day for 7-10 days. Preventive treatment courses are carried out 2-3 times a year.

For the prevention of post-extraction alveolitis: after tooth extraction, the hole is treated with Metrogyl DentaЃ gel, then the gel is applied 2-3 times a day for 7-10 days.

Side effect

With local application of the drug Metrogyl DentaЃ, dental gel, allergic reactions (skin rash, itching, urticaria, anaphylactic reactions, including anaphylactic shock), as well as headache, can be observed.

Overdose

Accidental or deliberate swallowing of a large amount of gel can cause increased side effects, mainly due to metronidazole (chlorhexidine is practically not absorbed from the gastrointestinal tract). There can be observed: nausea, vomiting, dizziness, in more severe cases - paresthesia and convulsions. Treatment: gastric lavage, symptomatic therapy if necessary.

Interaction with other medicinal products

When applied topically in the recommended doses, no systemic interaction of Metrogyl DentaЃ gel with other drugs has been identified.

special instructions

The use of Metrogyl DentaЃ does not replace hygienic teeth cleaning, therefore, during the course of treatment with the drug, teeth cleaning should be continued.

The drug should be kept out of the reach of children. If a child accidentally or intentionally swallows the drug, seek immediate medical attention.

If the medicinal product has become unusable or the expiration date has expired, do not throw it into waste water or outside! Place the medicine in a bag and put it in the trash can. These measures will help protect the environment!

Influence on the ability to drive vehicles and other mechanisms

There is no information about the effect of the drug on the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Release form

Dental gel

- 5 g, 10 g or 20 g in a plastic laminated tube, the neck of which is sealed with aluminum foil laminated with polyethylene and with a screw cap made of polypropylene. One tube in a cardboard box with instructions for use.

- 5 g, 10 g or 20 g in a plastic laminated tube, the neck of which is sealed with aluminum foil, laminated with polyethylene and with a screw cap made of polypropylene with a projection for foil perforation. One tube in a cardboard box with instructions for use.

Storage conditions

At a temperature not higher than 25 ? C.

Keep out of the reach of children.

Shelf life

3 years. Do not use after the expiration date.

Vacation conditions

Without recipe.

Manufacturer:

Unique Pharmaceutical Laboratories (a division of JB Chemicals & Pharmaceuticals Ltd.), India