Miramistin solution for topical application, 0.01%, 50 ml bottle with a spray nozzle

Composition Topical solution 0.01% colorless, transparent, foaming on shaking

1 l benzyldimethyl-myristoylamino-propylammonium chloride monohydrate 100 mg Excipients: purified water - up to 1 l

50 ml - polyethylene bottles (1) complete with urological applicator - cardboard packs

Pharmacological action Miramistin has a wide spectrum of antimicrobial action, including hospital strains resistant to antibiotics

The drug has a pronounced bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae, etc.), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp., Etc.), aerobic and anaerobic bacteria, determined microbial associations, including hospital strains with multidrug resistance to antibiotics

It has an antifungal effect on ascomycetes of the genus Aspergillus and the genus Penicillium, yeast (Rhodotorula rubra, Torulopsis gabrata, etc.) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare, Malassezia, etc.) (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, etc.), as well as other microorganisms in the form of pathogenic including fungal microflora with resistance to chemotherapy drugs

Possesses antiviral effect, is active against complex viruses (herpes viruses, human immunodeficiency virus and others)

Miramistin acts on sexually transmitted disease pathogens (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae and others)

Effectively prevents infection of wounds and burns.

It activates the regeneration processes.

Stimulates protective reactions at the site of application, by activating the absorption and digestion functions of phagocytes, potentiates the activity of the monocytic-macrophage system.

It has a pronounced hyperosmolar activity, as a result of which it relieves wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry scab.

Does not damage granulations and viable skin cells, does not inhibit edge epithelization

Does not possess local irritant and allergenic properties

Indications For use in surgery, traumatology: - prevention of suppuration and treatment of purulent wounds

- treatment of purulent-inflammatory processes of the musculoskeletal system

For use in obstetrics, gynecology: - prevention and treatment of suppuration of postpartum injuries, perineal and vaginal wounds, postpartum infections

- prevention and treatment of inflammatory diseases (vulvovaginitis, endometritis)

For use in combustiology: - treatment of superficial and deep burns of II and III A degree

- preparation of burn wounds for dermatoplasty

For use in dermatology, venereology: - treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet

- individual prevention of sexually transmitted diseases (including syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis)

For use in urology: - complex treatment of acute and chronic urethritis and specific urethroprostatitis (chlamydia, trichomoniasis, gonorrhea) and non-specific nature

For use in dentistry: - treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis

- hygienic processing of removable dentures

For use in otorhinolaryngology: - complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis

- complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis

Name ENG

MIRAMISTIN

Clinical and pharmacological group

Topical antiseptic

ATX code

Quaternary ammonium compounds

Dosage

0.01% x 50ml

Structure

Solution for topical application 0.01% colorless, transparent, foaming on shaking.

1 lbenzyldimethyl-myristoylamino-propylammonium chloride monohydrate 100 mg Excipients: purified water - up to 1 liter.

50 ml - polyethylene bottles (1) complete with urological applicator - cardboard packs.

Indications

Surgery, traumatology: prevention of suppuration and treatment of purulent wounds.

Treatment of purulent-inflammatory processes of the musculoskeletal system.

Obstetrics, gynecology: prevention and treatment of suppuration of postpartum injuries, perineal and vaginal wounds, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).

Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty.

Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet.

Individual prevention of sexually transmitted diseases (including syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis).

Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of a specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.

Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis.

Hygienic treatment of removable dentures.

Otorhinolaryngology: complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis.

In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Contraindications

Hypersensitivity to the drug.

INN / Active ingredient

Benzyldimethyl 3- (myristoylamino) propylammonium chloride monohydrate

Specifications

Scope of the drug

Gynecology

Release form

Solution

Manufacturer country

Russia

Package quantity, pcs

one

Vacation conditions

Without recipe

Brand name

Infamed

Components

urological applicator, spray nozzle

The amount of the dosage form in the primary package

50 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiseptic

Anatomical and therapeutic characteristics

D08AJ Quaternary ammonium compounds

Dosage form

Topical solution

Dosage (volume) of the substance in the preparation

0.01%

Expiration date in days

1095

Package weight, g

fifty

Category

:

Antibiotics

,

Antiseptics and disinfectants

,

Disinfectants

Mode of application

:

With purulent sinusitis - during puncture, the maxillary sinus is washed with a sufficient amount of the drug. < br> Tonsillitis, pharyngitis and laryngitis are treated by gargling and / or irrigation using a spray nozzle by pressing 3-4 times 3-4 times / day. The amount of the drug for 1 rinse is 10-15 ml < br> For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug 3-4 times / day. < br> When used in surgery, traumatology, combustiology with preventive and therapeutic purposes, irrigate the surface of wounds and burns, loosely tampon wounds and fistulous passages, fix gauze tampons moistened with the drug. The treatment procedure is repeated 2-3 times / day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug < br> When used in obstetrics,gynecology for the prevention of postpartum infection is used in the form of vaginal irrigation before childbirth (5-7 days), during childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours, for 5 days. For the convenience of vaginal irrigation, the use of a gynecological nozzle is recommended. Introduce the contents of the vial into the vagina with the help of a gynecological nozzle and irrigate women. When delivering women by cesarean section, immediately before the operation, the vagina is treated, during the operation - the uterine cavity and an incision on it, and in the postoperative period, tampons soaked in vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out in a course of 2 weeks by intravaginal administration of tampons with the drug,and also by the method of medicinal electrophoresis < br> For the prevention of sexually transmitted diseases, the drug is effective if it is applied no later than 2 hours after intercourse. Introduce the contents of the bottle with the urological applicator into the urethra for 2-3 minutes: men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml). For convenience, the use of a gynecological attachment is recommended. Treat the skin of the inner surfaces of the thighs, pubis, genitals. After the procedure, it is recommended not to urinate for 2 hours. < br> In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 1-2 times / day, the course of treatment is 10 days. < br> In acute pharyngitis and / or exacerbation of chronic tonsillitis irrigate the pharynx using a spray nozzle. Children aged 3-6:by pressing once on the head of the spray nozzle (3-5 ml for one irrigation), 3-4 times / day children aged 7-14 years by double pressing (5-7 ml per irrigation), 3-4 times / day children over 14 years old by pressing 3-4 times (10-15 ml per irrigation), 3-4 times / day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission < br> Rules for the use of the drug The drug is ready for use < br> Instructions for the use of packaging with a spray nozzle 1. Remove the cap from the bottle, also remove the urological applicator from the 50 ml bottle ... 2. Remove the supplied spray nozzle from the protective packaging. 3. Attach the spray nozzle to the bottle. 4. Activate the spray nozzle by pressing again < br> Instructions for use of the 50 ml or 100 ml pack with gynecological nozzle 1.Remove the cap from the vial < br> 2. Remove the attached gynecological attachment from the protective packaging < br> 3. Attach the gynecological attachment to the vial without removing the urological applicator.

Information on technical characteristics, delivery set, country of manufacture