Orlistat capsules 60mg, No. 42

It is taken orally at 120 mg during each main meal or within an hour after meals, usually no more than 3 times / day. Orlistat can be skipped if the food is low in fat.

orlistat

• Chronic malabsorption syndrome,

• hypersensitivity to orlistat.

pharmachologic effect

Lipase inhibitor. When taken orally, orlistat inhibits gastric and pancreatic lipases. As a result, the breakdown of dietary fats is disrupted and their absorption from the gastrointestinal tract decreases. With systematic use, this effect leads to a decrease in body weight in obese patients. Orlistat is practically not absorbed from the gastrointestinal tract and, therefore, practically does not have a resorptive effect.

Side effect

Possibly: oily discharge from the rectum, flatulence, 'fat' stools, frequent bowel movements, urge to defecate, fecal incontinence.

Application during pregnancy and lactation

Orlistat is used with extreme caution during pregnancy and lactation.

special instructions

It must be borne in mind that the frequency and severity of side effects increase with an increase in the content of fat in food. As the fat content of food decreases, the likelihood of side effects decreases. It is recommended that the amount of fat consumed per day is distributed fairly evenly across all meals. In the course of treatment, as the body weight decreases, it is possible to improve the course of pathological processes that are often associated with obesity, incl. arterial hypertension, diabetes mellitus, lipid metabolism disorders.

Drug interactions

It has been shown that orlistat leads to a decrease in the absorption of beta-carotene and a-tocopherol from the gastrointestinal tract.