Piperazine | Piperazine tablets 500 mg, 10 pcs.

packaging 10 pcs

Pharmacological action

Piperazine is an anthelmintic drug, effective in ascariasis and enterobiosis. It has a paralyzing effect on nematodes: disrupting the function of their neuromuscular system, causes muscle paralysis.

The severity of deworming drug is at the level of 90-95%, and with repeated use can be about 100%. Due to the fact that piperazine does not destroy roundworm, there is no danger of absorption of biological toxic products of their decay. Low toxicity.

Contraindications

Children under the age of 3 years (for this dosage form).

Hypersensitivity, organic diseases of the central nervous system, chronic renal failure.

Special instructions

Treatment of piperazine with adipate does not require a special diet or preparation of patients. Laxatives are prescribed only with a tendency to constipation.

During the treatment of enterobiasis, a strict hygiene regimen is observed.

Treatment can be done on an outpatient basis.

Composition

1 tablet contains:

Active ingredient: piperazine adipate (piperazine adipinate) - 500 mg

Excipients: talc, calcium stearate, corn starch, sodium carboxymethyl starch (sodium starch).

Dosage and Administration

Inside.

With ascariasis, adults and children over 15 years of age are prescribed 1.5 - 2 g, a daily dose of 3-4 g.

For children. A single and daily dose, respectively: from 3 years old - 0.3 and 0.6 g 4-5 years old - 0.5 and 1 g 6-8 years old - 0.75 and 1.5 g 9-12 years old - 1 and 2 g 13-15 years - 1.5 and 3 g

In the treatment of ascariasis prescribed 2 times a day for 1 hour or 0.5-1 hours after eating for 2 consecutive days.

According to another scheme - once (0.4-4 g depending on age) or 2 times 0.2-2 g. For the treatment of enterrbiasis is prescribed in the same doses as with ascariasis, for 5 consecutive days with 7-day intervals between courses. Conduct 1-3 courses of therapy.

To remove pinworms from the rectum, an enema of 1-3 glasses of water is placed between the courses of treatment at night, with 1/2 teaspoon of sodium bicarbonate added to it (1 cup).

Side effects

Nausea, abdominal pain of a spastic nature, headache.

In patients with renal failure, neurotoxic complications (muscle weakness, tremors, euphoria, hallucinations, blurred vision, impaired coordination of movements).

Drug Interactions

Enhances the severity of extrapyramidal disorders caused by chlorpromazine.

Overdose

Symptoms: tremor, muscle weakness.

Treatment: gastric lavage, intake of activated charcoal or other enterosorbents, administration of salt laxatives. If necessary - oxygen and transfusion therapy. In neurological symptoms, thiamine is administered.

Storage conditions

At a temperature not exceeding 25 РC.

Expiration date

4 years

Active ingredient

Piperazine

Conditions of release from

pharmacies by prescription

tablet dosage form of tablets



Possible product names

Piperazin tab 500mg N10 pack b / cc control (PARTY 200pcs)

Piperazin tablets 500 mg, 10 pcs.

Pharmstandard-Leksredstva, Russia