pyridoxine | Pyridoxine ampoules 5%, 1 ml, 10 pcs.

Packing

10 ampoules of 1 ml.

Pharmacological Action

Pyridoxine Hydrochloride - Vitamin B6. Phosphorylated and in the form of pyridoxalphosphate is a part of enzymes, catalyzing decarboxylation and transamination. It plays an important role in the metabolism of tryptophan, glutamic acid, cysteine, methionine, as well as in the transport of amino acids through the cell membrane. It is necessary for the activation of phosphorylase, for the formation of neurotransmitters, gamma-aminobutyric acid, glycine, serotonin. Participates in the exchange of vitamin B12, folic acid, in the synthesis of porphyrins, in the exchange of unsaturated fatty acids. It is used to activate metabolic processes in myofibrils, especially with myocardial hypoxia. The daily requirement for adults is 2–2.5 mg, for children from 6 months to 1 year — 0.5 mg, 1–1.5 years — 0.9 mg, 1.5–2 years — 1 mg, 3– 4 years old - 1.3 mg, 5-6 years old - 1.4 mg, 7-10 years old - 1.7 mg, 11-13 years old - 2 mg, for boys 14-17 years old - 2.2 mg, for girls 14-17 years - 1.9 mg.

Indications

B6-hypovitaminosis, toxicosis of pregnant women, sideroblastic anemia, leukopenia, central nervous system diseases (parkinsonism, small chorea, Little's disease, radiculitis, neuritis, neuralgia, Meniere's disease), sea and air sickness, atherosclerosis, atherosclerosis diabetes mellitus, seborrhea-like and non-seborrheic dermatitis, herpes zoster, neurodermatitis, psoriasis, exudative diathesis, use of isoniazid group preparations.

Contraindications

Hypersensitivity. With caution: peptic ulcer of the stomach and duodenum.

Composition

1 ampoule (1 ml) contains: pyridoxine hydrochloride 50 mg, water for and ektsy to 1 ml.

Dosage and Administration

Subcutaneously, intramuscularly and intravenously. Adults are usually prescribed 0.05-0.1 g per day in 1-2 doses, for children 0.02 g. The course of treatment for adults is 1 month, for children 2 weeks.

For the treatment of sideroblastic anemia - 0.1 g intramuscularly 2 times a week. It is advisable to take folic acid, cyanocobalamin, riboflavin at the same time.

With parkinsonism - 2 ml of a 5% solution per day intramuscularly. The course of treatment is 20-25 injections. After 2-3 months, the course is repeated.

In depressions of involutional age, 0.2 g per day is administered intramuscularly.

Side effects

Allergic reactions, increased acidity of gastric juice.

Drug interactions

Isoniazid, cycloserine, penicillamine reduce the effect. Pharmaceutically incompatible with vitamins B1 and B12. It weakens the antiparkinsonian activity of levodopa.

Storage conditions

In the dark place.

Expiration

3 years

Active ingredient srdlk p Pyridoxine

Terms and conditions

prescription

dosage form

injection solution

Indications

From anemia, From psoriasis, From psoriasis, From hypovitaminosis, Dermatitis, Radiculitis, Lumbago, Toxicosis of pregnant women, From hepatitis

Dalkhimpharm, Russia