Rehydron powder, No. 20

The contents of one sachet are dissolved in 1 liter of freshly boiled chilled drinking water, the prepared colorless solution is taken orally. If necessary, the solution may be administered through a nasogastric tube (in a hospital setting). The prepared solution should be stored in the refrigerator (at a temperature of 2 ? to 8 ? C); the solution should be consumed within 24 hours. In order not to disrupt the effect of the drug, no other components should be added to the solution.

Before starting treatment, the patient should be weighed to assess the loss of body weight and the degree of dehydration. Patient nutrition or breastfeeding during oral rehydration therapy should not be interrupted or should be continued immediately after rehydration therapy. During treatment with the drug, it is recommended to avoid eating foods rich in fats and simple carbohydrates (this can aggravate diarrhea).

To prevent dehydration, the use of the drug RegidronЃ should be started as soon as diarrhea begins. Usually the drug is required to be used no more than 3-4 days, treatment is stopped with the end of the diarrhea. If nausea or vomiting occurs, it is advisable to take the solution chilled in small portions (for example, teaspoons).

Fluid replacement

To replenish fluid, RehydronЃ is taken during the first 6-10 hours in an amount that is twice the loss of body weight caused by diarrhea. For example, if the body weight loss is 400 g, the volume of RegidronЃ solution is 800 ml. No other fluids are required during this phase. It is not recommended to eat during the first 4 hours of fluid replenishment. Vomiting may occur if large volumes are taken.

sodium chloride, potassium chloride, sodium citrate, dextrose.

• hypersensitivity to drug components; severe dehydration;

• coma;

• intestinal obstruction;

• severe vomiting;

• diarrhea due to cholera;

• glucose-galactose malabsorption.

pharmachologic effect

Rehydration agent for oral administration. RehydronЃ is used to correct electrolyte and fluid imbalances in diarrhea. Dextrose promotes the absorption of electrolytes, which helps to correct metabolic acidosis. The osmolarity of the solution is 282 mOsm / L, pH 8.2.

Pharmacokinetics

The pharmacokinetic properties of water, electrolytes and dextrose that make up the drug are similar to those found in the human body.

Side effect

Patients with normal renal function are at low risk of developing hypernatremia or excess water intake. If taken too quickly, vomiting may occur.

Application during pregnancy and lactation

In recommended doses, RehydronЃ can be prescribed during pregnancy and lactation.

Application for violations of liver function

Caution should be exercised in patients with impaired liver function.

Application for impaired renal function

Caution should be exercised in patients with impaired renal function. Patients with renal insufficiency should take into account that the preparation contains potassium.

Application in children

In children, other solutions with lower sodium and osmolarity should be used.

special instructions

Given the composition of the medicinal product, caution should be exercised in patients with diabetes mellitus, impaired liver or kidney function, and in patients on a diet low in salt (sodium and / or potassium). In patients with diabetes mellitus, kidney failure, and some other chronic diseases, diarrhea can cause a significant imbalance in fluid or glucose balance. In this regard, the treatment of diarrhea in these patients may require laboratory monitoring and hospitalization. If the patient's need for additional administration of electrolytes is not confirmed by laboratory tests, the recommended doses of the drug should not be exceeded. Severe dehydration (weight loss> 10%, cessation of urine output) should be treated with IV rehydration medications,after which it is allowed to start using the RegidronЃ solution. If necessary, intravenous administration of drugs or with severe dehydration or severe vomiting, with a decrease or cessation of urine excretion, RegidronЃ should be used with caution. In case of vomiting, wait 10 minutes after the end of the vomiting attack and give the solution to drink slowly, in small sips. The patient should consult a doctor if, during the use of the drug RegidronЃ, he has the following situations: delayed speech, irritability, rapid fatigue, drowsiness, stupor; ? the temperature rises above 39 ? C; ? bloody stools; ? incessant vomiting; ? diarrhea lasts more than 2 days; ? severe abdominal pain. With diarrhea that develops with cholera and a number of other severe intestinal infections,the use of RehydronЃ solution in order to replenish the loss of electrolytes may not be enough. Persons with renal insufficiency or on a diet low in potassium should take into account that the preparation contains potassium.

Use in pediatrics

In children, other solutions with lower sodium and osmolarity should be used. Influence on the ability to drive vehicles and control mechanisms RegidronЃ does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Overdose

Symptoms: with the introduction of a large volume or a highly concentrated solution of RegidronЃ (if the rules for preparing the solution are violated), hypernatremia may occur. Symptoms of hypernatremia include weakness, neuromuscular agitation, drowsiness, confusion, coma, and sometimes respiratory arrest. Patients with impaired renal function may experience hyperkalemia, manifested by an irregular heart rhythm, and weakness. Treatment: if you experience symptoms of an overdose, you should consult a doctor. Correction of water and electrolyte balance should be carried out on the basis of laboratory data.

Drug interactions

Interaction with other medicinal products has not been studied. The solution of the drug has a slightly alkaline reaction, therefore it can affect drugs, the absorption of which depends on the pH of the intestinal contents. Diarrhea itself can alter the absorption of many drugs that are absorbed in the small or large intestine, or drugs that are metabolized by enterohepatic circulation.