Rennie orange chewable tablets, # 12

• Symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, sour belching, recurrent pain in the stomach, a feeling of fullness or heaviness in the epigastric region, dyspepsia (including those caused by inaccuracies in diet, taking medications, alcohol abuse , coffee, nicotine);

• Dyspepsia of pregnant women.

The drug is taken orally.

Adults and children over the age of 12 years with the onset of symptoms 1-2 tab. should be chewed (or kept in the mouth until completely dissolved). If necessary, you can repeat taking the drug after 2 hours. The maximum daily dose is 11 tab.

Active substance:

calcium carbonate - 680 mg

magnesium carbonate basic - 80 mg

Excipients : sucrose - 475 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 33.14 mg, magnesium stearate - 10.66 mg, liquid paraffin - 5 mg, orange flavor (orange oil, maltodextrin, purified water) - 35.2 mg, sodium saccharinate - 2 mg.

• severe renal failure;

• hypercalcemia;

• hypophosphatemia;

• nephrocalcinosis;

• children under 12 years of age;

• deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption (for chewable tablets);

• hypersensitivity to the components of the drug.

Chewable tablets (menthol) from white to white with a light brown shade, square, with concave surfaces, engraved with 'RENNIE' on both sides, with a menthol scent.

Composition:

Active substance:

calcium carbonate - 680 mg

magnesium carbonate basic - 80 mg

Excipients : sucrose - 475 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 33.14 mg, magnesium stearate - 10.66 mg, light liquid paraffin - 5 mg, menthol flavor (peppermint oil, maltodextrin, gum arabic, silicon dioxide) - 13 mg, lemon flavor (lemon oil, maltodextrin, water) - 0.2 mg.

Chewable tablets (orange), white with a creamy shade, square, with concave surfaces, engraved with 'RENNIE' on both sides, with an orange scent.

Composition:

Active substance:

calcium carbonate - 680 mg

magnesium carbonate basic - 80 mg

Excipients : sucrose - 475 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 33.14 mg, magnesium stearate - 10.66 mg, liquid paraffin - 5 mg, orange flavor (orange oil, maltodextrin, purified water) - 35.2 mg, sodium saccharinate - 2 mg.

Sugar-free (mint) chewable tablets, white with a creamy shade, square, with concave surfaces, engraved with 'RENNIE' on both sides, with a mint scent.

Composition:

Active substance:

calcium carbonate - 680 mg

magnesium carbonate basic - 80 mg

Excipients : sorbitol - 400 mg, pregelatinized corn starch - 20 mg, potato starch - 13 mg, talc - 35.5 mg, magnesium stearate - 10.7 mg, liquid paraffin - 5 mg, mint flavor - 10 mg, sodium saccharinate - 800 ?g.

Clinical and pharmacological group: Antacid drug

Pharmaco-therapeutic group: Antacid

pharmachologic effect

Antacid drug. Contains calcium carbonate and magnesium carbonate, which provide fast and long-term neutralization of excess gastric acid hydrochloric acid, thereby providing a protective effect on the gastric mucosa.

The achievement of a therapeutic effect within 3-5 minutes is due to the good solubility of the tablets and the high calcium content.

Pharmacokinetics

Suction

As a result of the interaction of RennieЃ with gastric juice, soluble calcium and magnesium salts are formed in the stomach. The degree of absorption of calcium and magnesium from these compounds depends on the dose of the drug. Maximum absorption is 10% calcium and 15-20% magnesium.

Withdrawal

Small amounts of absorbed calcium and magnesium are excreted by the kidneys. In the intestine, insoluble compounds are formed from soluble salts, which are excreted in the feces.

Pharmacokinetics in special clinical situations

With impaired renal function, the concentration of calcium and magnesium in plasma may increase.

Indications

Symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, sour belching, recurrent pain in the stomach, a feeling of fullness or heaviness in the epigastric region, dyspepsia (including those caused by inaccuracies in diet, taking medications, abuse alcohol, coffee, nicotine);

• Dyspepsia of pregnant women.

Dosage regimen

The drug is taken orally.

Adults and children over the age of 12 years with the onset of symptoms 1-2 tab. should be chewed (or kept in the mouth until completely dissolved). If necessary, you can repeat taking the drug after 2 hours. The maximum daily dose is 11 tab.

Side effect

Allergic reactions: very rarely - rash, Quincke's edema, anaphylactic reactions.

If the recommended doses are observed, the drug is well tolerated.

Contraindications for use

• severe renal failure;

• hypercalcemia;

• hypophosphatemia;

• nephrocalcinosis;

• children under 12 years of age;

• deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption (for chewable tablets);

• hypersensitivity to the components of the drug.

Application during pregnancy and lactation

When used in recommended doses, the drug does not pose a danger to the fetus or child.

Application for impaired renal function

The drug is contraindicated in severe renal failure, nephrocalcinosis.

When prescribing the drug to patients with impaired renal function, the concentration of magnesium, phosphorus and calcium in the blood serum should be regularly monitored.

Patients with impaired renal function are not recommended to take the drug for a long time in high doses.

The use of RennieЃ in high doses may increase the risk of kidney stones.

Application in children

The drug is contraindicated in children under 12 years of age.

special instructions

When prescribing the drug to patients with impaired renal function, the concentration of magnesium, phosphorus and calcium in the blood serum should be regularly monitored.

Patients with impaired renal function are not recommended to take the drug for a long time in high doses.

The use of RennieЃ in high doses may increase the risk of kidney stones.

Each chewable tablet (menthol) / chewable tablet (orange) contains 475 mg of sucrose.

1 tablet of RennieЃ sugar-free (mint) contains 400 mg of sorbitol and can be prescribed for patients with diabetes mellitus.

In case of ineffectiveness of treatment, the patient should consult a doctor.

Influence on the ability to drive vehicles and mechanisms

Does not affect.

Overdose

Symptoms: long-term use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which can manifest as nausea, vomiting, muscle weakness.

Treatment: the drug should be canceled; the patient needs to see a doctor.

Drug interactions

The change in the acidity of gastric juice caused by the intake of antacids can lead to a decrease in the rate and degree of absorption of other drugs taken at the same time, therefore, drugs should be taken 1-2 hours before or after taking antacids.

With the simultaneous use of antacids, the absorption of antibiotics of the tetracycline group, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, phosphates, fluorides is reduced.

With simultaneous use with thiazide diuretics, the concentration of calcium in the blood serum should be regularly monitored.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25 ? C.

Shelf life

For chewable tablets (menthol) - 5 years, for chewable tablets (orange), sugar-free chewable tablets (mint) - 3 years.

Terms of sale

The drug is dispensed without a prescription.

Manufacturer:

BAYER AG (Germany)