Slabilen tablets p / o 5mg, No. 10

Constipation due to hypotension and sluggish motility of the colon.

Stool regulation for hemorrhoids, proctitis, anal fissures.

Preparation for surgical operations, instrumental and X-ray examinations.

Individual, depending on the patient's age and response to treatment. It is taken orally before bedtime.

Film-coated tablets of brownish-yellow color, round, biconvex, marked on both sides in the form of a depressed letter 'S'; in cross section, the core of the tablet is white or almost white.

1 tab.

sodium picosulfate 15 mg

Excipients: potato starch 82.92 mg, lactose monohydrate 175.35 mg, povidone 8.88 mg, magnesium stearate 2.85 mg.

• Intestinal obstruction

• strangulated hernia,

• acute inflammatory diseases of the abdominal organs,

• peritonitis,

• abdominal pain of unknown origin,

• bleeding from the gastrointestinal tract,

• uterine bleeding

• cystitis,

• spastic constipation

• I trimester of pregnancy,

• severe dehydration

• hypersensitivity to sodium picosulfate.

pharmachologic effect

Laxative. Under the influence of intestinal microorganisms, it is hydrolyzed to form an active form, which irritates the receptors of the intestinal mucosa and increases its peristalsis.

Pharmacokinetics

After oral administration, it is not absorbed from the gastrointestinal tract and does not undergo hepatic-intestinal circulation.

Side effect

Possibly: diarrhea, which can lead to excessive loss of fluid and electrolytes, weakness, seizures, arterial hypotension, abdominal pain.

Application during pregnancy and lactation

Contraindicated in the first trimester of pregnancy. It should be used in the II and III trimester of pregnancy only if the intended benefit to the mother outweighs the possible risk to the fetus. If necessary, use during lactation should stop breastfeeding.

Application in children

Contraindicated in children under 4 years of age.

special instructions

It has no taste, so it can be added to food for children. Do not use daily without medical supervision for more than 10 days.

Drug interactions

With simultaneous use with broad-spectrum antibiotics, it is possible to reduce the laxative effect of sodium picosulfate.

With simultaneous use with diuretics, with corticosteroids, an increase in the risk of electrolyte disturbances is possible.

The electrolyte imbalance that occurs while taking sodium picosulfate in high doses can lead to a deterioration in the tolerance of cardiac glycosides when used simultaneously.