Terbinafine, Urea | Fungoterbine Neo cream 15 g

Special Price $19.60 Regular Price $27.00
In stock
SKU
BID483526
Description

Cream of white or almost white color with a subtle smell.
Description

Cream of white or almost white color with a subtle smell.

Packaging

15 g - aluminum tubes (1) - packs of cardboard.

Pharmacological action

Terbinafine - active substance Fungoterbina® NEO, represents allylamine and has a wide spectrum of antifungal action. Terbinafine disrupts the ergosterol biosynthesis in fungi in the early stages. This leads to a deficiency of ergosterol and to intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus. This enzyme does not belong to the cytochrome P450 system, so terbinafine does not affect the metabolism of hormones or other drugs. Terbinafine has a fungicidal effect against dermatophytes, molds and some dimorphic fungi. Activity against yeast-like fungi, depending on their type, can be fungicidal or fungistatic. Urea - the second active component of Fungoterbine® NEO, has a softening, exfoliating and moisturizing effect, it is able to increase dermatopenrance (penetration into the skin) and create high concentrations of terbinafine in the skin. Urea promotes water binding and softens the stratum corneum.

Indications

Treatment and prevention of fungal diseases: Fungal infections of the skin caused by dermatophytes such as Trychophyton (e.g. T.rubrum, T.mentagrophytes, T.verrucosum, T.violaceum), Microsporum canis and Epidermophyton floccosum. Skin infections caused by yeast fungi of the genus Candida (e.g. Candida albicans). Multi-colored lichen (Pityrosporum versicolor) caused by Pityrosporum orbiculare (also known as Malassezia furfur).

Contraindications

Hypersensitivity to the components of the drug, children (up to 2 years). Precautions Hepatic and / or renal failure, alcoholism, blood diseases, tumors, metabolic diseases, vascular pathologies of the extremities.

Use during pregnancy and lactation

In experimental studies, no teratogenic properties of terbinafine were detected. The use of the drug during pregnancy is possible in cases where the potential benefit to the mother outweighs the risk to the fetus. Use the drug with caution in lactation.

Special instructions

A decrease in the severity of clinical manifestations is usually observed in the early days of treatment. In the case of irregular treatment or premature termination of it, there is a risk of a renewed infection. In the absence of signs of improvement after 1-2 weeks of therapy, the diagnosis should be verified. The cream is intended for external use only. Avoid contact with the mucous membrane of the eyes, nose, and mouth. If the drug enters the mucous membrane, rinse with water and consult a doctor if necessary.

Composition of

1 g of cream contains:

Active ingredient: clotrimazole 10 mg

Excipients: benzyl alcohol, cetostearyl alcohol, eutanol G, polysorbate 60, span 60, synthetic elbrot, Purified water

Liquid paraffin

Benzyl alcohol

Methyl parahydroxybenzoate (methyl paraben)

Propyl parahydroxybenzoate (propyl paraben)

Butylhydroxytoluene

Sodium dihydrogen phosphate 6 hydrofluphosphate cream contains: Active substances: Terbinafine hydrochloride in terms of 100% substance - 0.01 g, urea - 0.10 g Excipients: Butylhydroxytoluene (dibunol), macrogol cetostearate (EumulginΠB 2), cetostearyl alcohol [cetyl alcohol 60%, stearyl alcohol 40%], poloxamer (emuxol-268), imidourea (Germall?), propylene glycol, liquid paraffin (medical vaseline oil), purified water - up to 1 g.

Dosage and administration

The drug is applied to the skin once or twice a day. Before applying the cream, it is necessary to clean and dry the affected areas. The cream is applied in a thin layer on the affected skin and rubbed lightly. To increase the effectiveness of treatment, the use of occlusive dressings is possible. For infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the place of application of the cream can be covered with gauze, especially at night. The average duration of treatment: Dermatomycosis of the trunk, legs: 1 week 1 time per day. Dermatomycosis of the feet: 1 week 1 time per day. Candidiasis of the skin: 1 or 2 times a day for 1-2 weeks. Multi-colored lichen: 1 or 2 times a day for 2 weeks.

Side effects

In rare cases, redness has been noted, a sensation of itching or burning at the place of application of the cream, however, these phenomena rarely led to the need to stop treatment. The above symptoms should be distinguished from allergic reactions, for example, urticaria, which rarely occur, however, when they occur, it is necessary to stop treatment.

Storage conditions

At a temperature not exceeding 20 РC. Keep out of the reach of children.

Expiration

2 years. Do not use the product after the expiry date stated on the package.

Active ingredient

Terbinafine, Urea

Dosage form

Creams

Nizhpharm, Russia

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