Tiloron tablets 125mg, No. 10

• As part of complex therapy: viral hepatitis A, B and C;

• infections caused by Herpes simplex viruses type 1 and 2, Varicella zoster, cytomegalovirus;

• infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, uveoencephalitis);

• urogenital and respiratory chlamydia;

• non-gonococcal urethritis;

• pulmonary tuberculosis.

• Treatment and prevention of influenza and other acute respiratory viral infections.

When taken orally, the daily dose is 125-250 mg. The frequency of admission and the duration of use depend on the indications and treatment regimen.

Tablets, film-coated from yellow to orange, round, biconvex, on the cross-section of the tablets are visible: the film coat and the core are orange, inclusions of white or orange in different shades are allowed.

1 tab.

tilorone dihydrochloride 125 mg

Excipients: microcrystalline cellulose (MKTs-101) - 148 mg, croscarmellose sodium - 12 mg, povidone K25 - 12 mg, magnesium stearate - 3 mg.

• Pregnancy,

• lactation (breastfeeding),

• children under 7 years old,

• hypersensitivity to tilorone.

pharmachologic effect

Low molecular weight inducer of endogenous interferon. It is a synthetic compound of the aromatic series, belongs to the class of fluorenones. Stimulates the formation of alpha, beta, gamma interferons in the body. The main structures producing interferon in response to the administration of tilorone are intestinal epithelial cells, hepatocytes, T-lymphocytes, granulocytes. After oral administration, the maximum production of interferon is determined in the intestine-liver-blood sequence after 4-24 hours. In human leukocytes, tilorone induces the formation of interferon, the level of which in the blood is 250 U / ml.

It has an immunomodulatory effect: stimulates bone marrow stem cells, increases antibody production depending on the dose, increases the ratio of high-avidity / low-avidity antibodies, reduces the degree of immunosuppression, restores the ratio of T-helpers / T-suppressors.

Side effect

Possibly: short-term chills, allergic reactions.

In some cases: dyspeptic symptoms.

Application during pregnancy and lactation

Tiloron is contraindicated for use during pregnancy and lactation (breastfeeding).

Application in children

Contraindicated in children under 7 years of age.

special instructions

It is not recommended to use tilorone in doses exceeding the recommended ones in order to avoid possible short-term depletion of immunocompetent cells.

As part of the complex therapy of neuroviral infections, tilorone is used under the supervision of a physician.

Drug interactions

Tiloron is compatible with antibiotics, traditional treatments for viral and bacterial diseases.