Vermox tablets 100mg, No. 6

• Enterobiasis,

• ascariasis,

• ankylostomiasis,

• strongyloidosis,

• trichocephalosis,

• trichinosis,

• teniasis,

• echinococcosis,

• alveococcosis,

• capillariasis,

• gnatostomosis,

• mixed helminthiases.

Inside with a little water.

Adults and children over 10 years of age with enterobiasis - once, 100 mg.

Children aged 2 to 10 years, once - 25-50 mg.

In the case of a high probability of re-invasion, take again after 2-4 weeks at the same dose.

It is recommended that all family members be treated simultaneously.

With ascariasis, trichocephalosis, ankylostomiasis, teniasis, strongyloidiasis and mixed helminthiasis - in the morning and evening, 100 mg for 3 days.

With trichinosis, 3 times a day, 200-400 mg for 3 days, and from 4 to 10 days - 3 times, 400-500 mg.

With echinococcosis in the first 3 days - 500 mg 2 times a day, in the next 3 days the dose is increased to 500 mg 3 times a day, then the dose is increased to the maximum (at the rate of 25-30 mg / kg / day) and taken in 3-4 receptions.

Active ingredient: mebendazole - 100mg

Auxiliary components: sodium lauryl sulfate, colloidal silicon dioxide, magnesium stearate, sodium saccharinate, talc, corn starch, lactose monohydrate.

• Hypersensitivity

• nonspecific ulcerative colitis,

• Crohn's disease,

• liver failure,

• children's age (up to 2 years old),

• pregnancy,

• lactation period.

Trade name: VERMOX

International non-proprietary name:

mebendazole

Chemical name: methyl- (5-benzoyl-1H-benzimidazol-2 yl) -carbamate

Dosage form:

pills

Composition

Active ingredient: mebendazole - 100mg

Auxiliary components: sodium lauryl sulfate, colloidal silicon dioxide, magnesium stearate, sodium saccharinate, talc, corn starch, lactose monohydrate.

Description:

Tablets of a flat-cylindrical shape, white or almost white, beveled, with a slight characteristic odor, with the inscription 'VERMOX' on one side and with a line on the other.

Pharmacotherapeutic group:

Anthelmintic agent

pharmachologic effect

Anthelmintic drug with a broad spectrum of action, most effective for enterobiasis and trichocephalosis. Causing irreversible disruption of glucose utilization, it depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of adenosine triphosphate (ATP).

Pharmacokinetics.

Practically not absorbed in the intestine. The half-life is 2.5-5.5 hours. Communication with plasma proteins - 90%. Unevenly distributed throughout the organs, accumulates in adipose tissue, liver, helminth larvae. In the liver, it is metabolized to a 2-amino derivative. More than 90% of the dose is excreted in the feces unchanged. The absorbed part (5-10%) is excreted by the kidneys.

Indications for use:

• Enterobiasis,

• ascariasis,

• ankylostomiasis,

• strongyloidosis,

• trichocephalosis,

• trichinosis,

• teniasis,

• echinococcosis,

• alveococcosis,

• capillariasis,

• gnatostomosis,

• mixed helminthiases.

Contraindications:

• Hypersensitivity

• nonspecific ulcerative colitis,

• Crohn's disease,

• liver failure,

• children's age (up to 2 years old),

• pregnancy,

• lactation period.

Method of administration and dosage:

Inside with a little water.

Adults and children over 10 years of age with enterobiasis - once, 100 mg.

Children aged 2 to 10 years, once - 25-50 mg.

In the case of a high probability of re-invasion, take again after 2-4 weeks at the same dose.

It is recommended that all family members be treated simultaneously.

With ascariasis, trichocephalosis, ankylostomiasis, teniasis, strongyloidiasis and mixed helminthiasis - in the morning and evening, 100 mg for 3 days.

With trichinosis, 3 times a day, 200-400 mg for 3 days, and from 4 to 10 days - 3 times, 400-500 mg.

With echinococcosis in the first 3 days - 500 mg 2 times a day, in the next 3 days the dose is increased to 500 mg 3 times a day, then the dose is increased to the maximum (at the rate of 25-30 mg / kg / day) and taken in 3-4 receptions.

Side effects:

Dizziness, nausea, abdominal pain.
When used in high doses for a long time, vomiting, diarrhea, headache, allergic reactions (skin rash, urticaria, angioedema), increased activity of hepatic transaminases, hypercreatininemia, leukopenia, anemia, eosinophilia, hair loss, hematuria, cylindruria.

Overdose:

Symptoms are abdominal pain, nausea, vomiting, diarrhea. When used in high doses for a long time, reversible liver dysfunction, hepatitis, neutropenia.
Treatment is necessary to remove the drug from the stomach, causing vomiting or doing gastric lavage, taking activated charcoal.

Interaction with other drugs:

Reduces the need for insulin in diabetic patients. Joint administration with lipophilic substances should be avoided.
Cimetidine can increase the concentration in the blood, carbamazepine and other metabolism inducers - lower it.

Special instructions.

With prolonged use, it is necessary to monitor the peripheral blood picture, liver and kidney function.
During the day after ingestion, the use of ethanol, fatty foods is prohibited, a laxative is not prescribed.
Be sure to periodically examine smears of the anal area and feces after the end of treatment, therapy is considered effective in the absence of helminths or their eggs for 7 consecutive days.

Release form

100 mg of mebendazole per tablet.
6 tablets in a blister of PVC and aluminum foil 1 blister with instructions for use is placed in a cardboard box.

Shelf life

5 years.
Do not use after the expiration date printed on the package.

Storage conditions

Store at a temperature of 15-30 ? C, out of the reach of children.

Terms of dispensing from pharmacies
Prescription.