Wormin tablets 100mg, No. 24

• Enterobiasis,

• ascariasis,

• ankylostomiasis,

• strongyloidosis,

• trichocephalosis,

• trichinosis,

• teniasis,

• echinococcosis,

• multiple nematodes,

• alveococcosis,

• capillariasis,

• gnatostomosis,

• mixed helminthiases.

Inside with a little water.

Adults and children over 10 years of age with enterobiasis - once 100 mg.

Children aged 2 to 10 years - a single dose of 25-50 mg.

In the case of a high probability of re-invasion, take again after 2-4 weeks at the same dose.

It is recommended that all family members be treated simultaneously.

With ascariasis, trichocephalosis, ankylostomiasis, teniasis, strongyloidiasis and mixed helminthiasis - in the morning and evening, 100 mg for 3 days.

With trichinosis - 3 times a day, 200-400 mg for 3 days, and from 4 to 10 days - 3 times 400-500 mg.

With echinococcosis in the first 3 days - 500 mg 2 times a day, in the next 3 days the dose is increased to 500 mg 3 times a day; in the future, the dose is increased to the maximum (at the rate of 25-30 mg / kg / day) and taken in 3-4 doses.

1 tablet contains

Active ingredient: mebendazole 100 mg

Auxiliary components: calcium hydrogen phosphate, corn starch, gelatin, purified talc, magnesium stearate, sodium lauryl sulfate, vanillin (Monsanto), sunset yellow dye, orange DC116A.

• Hypersensitivity

• nonspecific ulcerative colitis,

• Crohn's disease,

• liver failure,

• children's age (up to 2 years old),

• pregnancy,

• lactation period.

Trade name: VORMIN

International non-proprietary name:

mebendazole

Chemical name: methyl 5-benzoyl-2-benzimidazole carbamate

Dosage form:

pills

Description:

round, flat, light orange tablets with beveled edges and vanillin odor.

Composition: 1 tablet contains

Active ingredient: mebendazole 100 mg

Auxiliary components: calcium hydrogen phosphate, corn starch, gelatin, purified talc, magnesium stearate, sodium lauryl sulfate, vanillin (Monsanto), sunset yellow dye, orange DC116A.

Pharmacotherapeutic group:

Anthelmintic agent.

pharmachologic effect

Broad-spectrum anthelmintic drug; most effective for enterobiasis and trichocephalosis. Causing irreversible disruption of glucose utilization, it depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of adenosine triphosphate (ATP).

Pharmacokinetics

Practically not absorbed in the intestine. The half-life is 2.5-5.5 hours. Communication with plasma proteins - 90%. Unevenly distributed throughout the organs, accumulates in adipose tissue, liver, helminth larvae. In the liver, it is metabolized to a 2-amino derivative. More than 90% of the dose is excreted in the feces unchanged. The absorbed part (5-10%) is excreted by the kidneys.

Indications for use:

• Enterobiasis,

• ascariasis,

• ankylostomiasis,

• strongyloidosis,

• trichocephalosis,

• trichinosis,

• teniasis,

• echinococcosis,

• multiple nematodes,

• alveococcosis,

• capillariasis,

• gnatostomosis,

• mixed helminthiases.

Contraindications:

• Hypersensitivity

• nonspecific ulcerative colitis,

• Crohn's disease,

• liver failure,

• children's age (up to 2 years old),

• pregnancy,

• lactation period.

Method of administration and dosage:

Inside with a little water.

Adults and children over 10 years of age with enterobiasis - once 100 mg.

Children aged 2 to 10 years - a single dose of 25-50 mg.

In the case of a high probability of re-invasion, take again after 2-4 weeks at the same dose.

It is recommended that all family members be treated simultaneously.

With ascariasis, trichocephalosis, ankylostomiasis, teniasis, strongyloidiasis and mixed helminthiasis - in the morning and evening, 100 mg for 3 days.

With trichinosis - 3 times a day, 200-400 mg for 3 days, and from 4 to 10 days - 3 times 400-500 mg.

With echinococcosis in the first 3 days - 500 mg 2 times a day, in the next 3 days the dose is increased to 500 mg 3 times a day; in the future, the dose is increased to the maximum (at the rate of 25-30 mg / kg / day) and taken in 3-4 doses.

Side effects:

Dizziness, nausea, abdominal pain.
When used in high doses for a long time: vomiting, diarrhea, headache, allergic reactions (skin rash, urticaria, angioedema), increased activity of hepatic transaminases, hypercreatininemia, leukopenia, anemia, eosinophilia, hair loss, hematuria, cylinduria ...

Overdose:

Symptoms: abdominal pain, nausea, vomiting, diarrhea. When used in high doses for a long time: reversible liver dysfunction, hepatitis, neutropenia.
Treatment: it is necessary to remove the drug from the stomach by causing vomiting or by doing gastric lavage, taking activated charcoal.

Interaction with other drugs:

Reduces the need for insulin in diabetic patients. Joint administration with lipophilic substances should be avoided.
Cimetidine can increase the concentration in the blood, carbamazepine and other metabolism inducers - lower it.

Special instructions:

With prolonged use, it is necessary to monitor the peripheral blood picture, liver and kidney function.
During the day after ingestion, the use of ethanol, fatty foods is prohibited, a laxative is not prescribed.
Periodic examination of smears of the anal area and feces after the end of treatment is mandatory: therapy is considered effective in the absence of helminths or their eggs for 7 consecutive days.

Release form

6 tablets in PVC / aluminum blister.
1 or 4 blisters together with instructions for use are packed in a cardboard box

Storage conditions

At a temperature not exceeding 25 ? C, out of the reach of children.

Shelf life

4 years.
Do not use after the expiration date printed on the package.

Conditions of dispensing from pharmacies

On prescription.